Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A, His-tagged

Cat.No. : PPP1R14A-110H
Product Overview : Recombinant His tagged PPP1R14A was expressed in E.coli and purified by using conventional chromatography techniques (167 aa, 18 kDa).
  • Specification
  • Gene Information
  • Related Products
Cat. No. : PPP1R14A-110H
Description : PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization.
Source : E.coli.
Formulation : Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 2 mM EDTA, 10% glycerol.
Molecular Weight : 18 kDa (167 aa).
Purity : > 95% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequence : MGSSHHHHHH SSGLVPRGSH MAAQRLGKRV LSKLQSPSRA RGPGGSPGGL QKRHARVTVK YDRRELQRRL DVEKWIDGRL EELYRGMEAD MPDEINIDEL LELESEEERS RKIQGLLKSC GKPVEDFIQE LLAKLQGLHR QPGLRQPSPS HDGSLSPLQD RARTAHP
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : PPP1R14A
Synonyms : PPP1R14A; protein phosphatase 1, regulatory (inhibitor) subunit 14A; CPI17; CPI-17; PPP1INL; 17 kDa PKC-potentiated inhibitory protein of PP1; PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A; 17-KDa protein; 17-kDa PKC-potentiated inhibitory protein of PP1; PKC-potentiated inhibitory protein of PP1.
Gene ID : 94274
mRNA Refseq : NM_033256.1
Protein Refseq : NP_150281.1
MIM : 608153
UniProt ID : Q96A00
Chromosome Location : 19q13.1
Function : phosphoprotein phosphatase inhibitor activity; protein binding.

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All PPP1R14A Products

Required fields are marked with *

My Review for All PPP1R14A Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends