Recombinant Human Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A, His-tagged
Cat.No. : | PPP1R14A-110H |
Product Overview : | Recombinant His tagged PPP1R14A was expressed in E.coli and purified by using conventional chromatography techniques (167 aa, 18 kDa). |
- Specification
- Gene Information
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Cat. No. : | PPP1R14A-110H |
Description : | PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization. |
Source : | E.coli. |
Formulation : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 2 mM EDTA, 10% glycerol. |
Molecular Weight : | 18 kDa (167 aa). |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Sequence : | MGSSHHHHHH SSGLVPRGSH MAAQRLGKRV LSKLQSPSRA RGPGGSPGGL QKRHARVTVK YDRRELQRRL DVEKWIDGRL EELYRGMEAD MPDEINIDEL LELESEEERS RKIQGLLKSC GKPVEDFIQE LLAKLQGLHR QPGLRQPSPS HDGSLSPLQD RARTAHP |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | PPP1R14A |
Synonyms : | PPP1R14A; protein phosphatase 1, regulatory (inhibitor) subunit 14A; CPI17; CPI-17; PPP1INL; 17 kDa PKC-potentiated inhibitory protein of PP1; PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A; 17-KDa protein; 17-kDa PKC-potentiated inhibitory protein of PP1; PKC-potentiated inhibitory protein of PP1. |
Gene ID : | 94274 |
mRNA Refseq : | NM_033256.1 |
Protein Refseq : | NP_150281.1 |
MIM : | 608153 |
UniProt ID : | Q96A00 |
Chromosome Location : | 19q13.1 |
Function : | phosphoprotein phosphatase inhibitor activity; protein binding. |
Products Types
◆ Recombinant Protein | ||
Ppp1r14a-5061M | Recombinant Mouse Ppp1r14a Protein, Myc/DDK-tagged | +Inquiry |
PPP1R14A-4274R | Recombinant Rat PPP1R14A Protein, His (Fc)-Avi-tagged | +Inquiry |
PPP1R14A-7006M | Recombinant Mouse PPP1R14A Protein, His (Fc)-Avi-tagged | +Inquiry |
PPP1R14A-4615R | Recombinant Rat PPP1R14A Protein | +Inquiry |
PPP1R14A-6702H | Recombinant Human PPP1R14A Protein (Met1-Pro147), C-His tagged | +Inquiry |
◆ Lysates | ||
PPP1R14A-2945HCL | Recombinant Human PPP1R14A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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