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Recombinant Zebrafish ANKRD12

Cat.No. : ANKRD12-10497Z
Product Overview : Recombinant Zebrafish ANKRD12 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Zebrafish
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC.
Storage Buffer : PBS buffer
Gene Name : ankrd12 ankyrin repeat domain 12 [ Danio rerio (zebrafish) ]
Official Symbol : ANKRD12
Gene ID : 393119
mRNA Refseq : NM_200150
Protein Refseq : NP_956444
UniProt ID : Q803C4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (22)

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Does ANKRD12 have any post-translational modifications? 01/09/2023

The post-translational modifications of ANKRD12 have not been extensively characterized. Future research may uncover potential modifications such as phosphorylation or acetylation.

Does ANKRD12 have any known functional domains besides the ankyrin repeat domains? 12/28/2022

Yes, ANKRD12 contains ankyrin repeat domains as well as a LEM domain, which is involved in nuclear membrane association.

Is ANKRD12 implicated in neuronal development or function? 10/30/2022

There is limited evidence suggesting a potential role for ANKRD12 in neuronal development and function. Further studies are needed to fully understand the involvement of ANKRD12 in these processes.

Is there any evidence suggesting a role for ANKRD12 in cancer development or progression? 02/01/2022

Currently, there is limited information regarding the involvement of ANKRD12 in cancer development or progression. However, some studies have reported altered expression of ANKRD12 in certain types of cancer, such as hepatocellular carcinoma and colorectal cancer. Further research is needed to fully understand the relationship between ANKRD12 and cancer.

Are there any known orthologs or paralogs of ANKRD12? 12/13/2021

Yes, ANKRD12 has orthologs in various species, including mice, rats, and zebrafish. Paralogs of ANKRD12 within the same genome have not been extensively studied.

Has ANKRD12 been implicated in any other diseases or conditions besides KBG syndrome? 11/24/2021

KBG syndrome is the primary condition associated with mutations in the ANKRD12 gene. However, additional research is ongoing, and future studies may uncover other diseases or conditions in which ANKRD12 plays a role.

Can ANKRD12 be targeted for therapeutic purposes? 07/03/2021

As of now, there are no known therapeutic interventions specifically targeting ANKRD12. However, further research into its functions and potential involvement in diseases may lead to the development of targeted therapies in the future.

Is ANKRD12 conserved across different species? 05/27/2021

Yes, ANKRD12 is highly conserved across diverse species, indicating its functional importance. The conservation suggests potential conserved roles in cellular processes throughout evolution.

Are there any existing animal models for studying ANKRD12 function? 03/04/2021

Currently, there are no reported animal models specifically generated to study ANKRD12 function. However, the use of knockout or knockdown models for ANKRD12 in various organisms may provide valuable insights into its physiological roles and potential effects on development or disease.

Is ANKRD12 essential for cell viability or development? 01/12/2020

Recent studies suggest that ANKRD12 is not essential for cell viability, but it may play a role in proper development, particularly in certain tissues or organ systems.

Can ANKRD12 be regulated by post-translational modifications? 12/11/2019

Yes, ANKRD12 can undergo post-translational modifications that may influence its function. For instance, phosphorylation of ANKRD12 by kinases such as PKC and CK2 has been reported to regulate its subcellular localization and interaction with other proteins. However, more research is needed to fully understand the extent and functional consequences of post-translational modifications on ANKRD12.

Are there any known interacting proteins or pathways associated with ANKRD12? 06/25/2019

ANKRD12 has been shown to interact with several proteins and participate in various cellular pathways. Some known interacting proteins include HIRA, CHD7, SET, p300, and RuvBL2. Additionally, ANKRD12 has been implicated in pathways related to chromatin remodeling, cellular senescence, and DNA replication.

Are there any known genetic disorders associated with mutations in the ANKRD12 gene? 10/28/2018

es, mutations in the ANKRD12 gene have been associated with a rare genetic disorder called KBG syndrome. Symptoms of KBG syndrome can vary but often include intellectual disability, short stature, dental abnormalities, and distinctive facial features.

Has ANKRD12 been studied in the context of neurodevelopmental disorders? 10/07/2018

Although ANKRD12 has not been extensively studied in the context of neurodevelopmental disorders, mutations in the ANKRD12 gene have been associated with developmental delay and intellectual disability, suggesting its potential involvement in neurodevelopmental processes.

Are there any known inhibitors or activators of ANKRD12? 08/14/2018

Currently, there are no known specific inhibitors or activators of ANKRD12. Future research may identify compounds or molecules that modulate its activity.

Is ANKRD12 involved in any signal transduction pathways? 05/05/2018

Current research suggests that ANKRD12 is not directly involved in signal transduction pathways. However, it may have indirect effects on gene expression and cellular processes through its interaction with other proteins.

Can ANKRD12 act as a transcriptional regulator? 08/11/2017

Yes, ANKRD12 has been shown to interact with transcriptional co-regulatory factors and may participate in the regulation of gene expression. However, the specific mechanisms by which ANKRD12 modulates transcriptional activity require further investigation.

How can the function of ANKRD12 be investigated? 12/24/2016

Functional studies of ANKRD12 can be conducted using techniques like gene knockdown or overexpression, protein-protein interaction assays, ChIP-seq, RNA-seq, and immunofluorescence microscopy.

Are there any known protein interactions of ANKRD12? 10/22/2016

ANKRD12 has been shown to interact with various proteins involved in chromatin remodeling, transcriptional regulation, and nuclear envelope organization. Examples include LEM domain-containing proteins and transcriptional co-regulatory factors.

What are the molecular functions attributed to ANKRD12? 10/21/2016

ANKRD12 has been implicated in diverse molecular functions, such as protein-protein interaction, chromatin remodeling, transcriptional regulation, DNA replication, and nuclear envelope organization.

Is ANKRD12 associated with any specific biological processes or pathways? 09/16/2016

ANKRD12 is implicated in diverse biological processes, such as chromatin organization, DNA replication, transcriptional regulation, and nuclear envelope assembly.

Is ANKRD12 expressed during embryonic development? 08/30/2016

ANKRD12 has been reported to be expressed during embryonic development in various tissues and organs. Its expression pattern suggests potential roles in processes such as organogenesis and tissue maturation.

Customer Reviews (5)

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Reviews
08/09/2022

    the protein's high quality ensures accurate and reliable results, enabling precise analysis and interpretation of experimental data.

    03/03/2022

      The ANKRD12 protein offers several advantageous features that make it an ideal choice for researchers conducting trials.

      11/29/2019

        The manufacturer of the ANKRD12 protein plays a crucial role in supporting researchers during their trials.

        10/29/2018

          the ANKRD12 protein demonstrates exceptional stability, allowing for prolonged storage and usage without compromising its integrity.

          04/06/2018

            By choosing the ANKRD12 protein and partnering with the manufacturer, researchers can confidently conduct their trials, achieve reliable results, and contribute to groundbreaking discoveries.

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