"RAB5A" Related Products

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Recombinant Human RAB5A

Cat. No. : RAB5A -374H
Product Overview : Recombinant human Rab5a was expressed in E.coli and purified by using conventional chromatography techniques,23 kDa ( 215 aa).
Description : Rab5a is a member of RAS oncogene family. The small GTPase, Rab5a is a crucial regulatory component of the endocytic pathway. Activation of Rab5a is mediated by GDP-GTP exchange factors (GEFs) that generate the Rab5-GTP complex.
Sequences of amino acids : MASRGATRPN GPNTGNKICQ FKLVLLGESA VGKSSLVLRF VKGQFHEFQE STIGAAFLTQ TVCLDDTTVK FEIWDTAGQE RYHSLAPMYY RGAQAAIVVY DITNEESFAR AKNWVKELQR QASPNIVIAL SGNKADLANK RAVDFQEAQS YADDNSLLFM ETSAKTSMNV NEIFMAIAKK LPKNEPQNPG ANSARGRGVD LTEPTQPTRN QCCSN
Formulation : Liquid in 20mM Tris-HCl buffer (pH 8.0)
Purity : > 95% by SDS - PAGE
Concentration : 1 mg/ml (determined by Bradford assay)
Endotoxin Level : < 1.0 EU per 1ug of protein (determined by LAL method)
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : RAB5A RAB5A, member RAS oncogene family [ Homo sapiens ]
Synonyms : RAB5A; RAB5A, member RAS oncogene family; RAB5; RAS-associated protein RAB5A
Gene ID : 5856
mRNA Refseq : NM_004162
Protein Refseq : NP_004153
MIM : 179512
UniProt ID : P20339
Chromosome Location : 3p24-p22
Pathway : Amyotrophic lateral sclerosis (ALS)
Function : GTP binding; GTPase activity; guanyl nucleotide binding; nucleotide binding; protein binding

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