Recombinant Human RAB5A

• Cat.No.: RAB5A-374H
• Product Overview: Recombinant human Rab5a was expressed in E.coli and purified by using conventional chromatography techniques,23 kDa ( 215 aa).

Specification

• Cat. No.: RAB5A -374H
• Description: Rab5a is a member of RAS oncogene family. The small GTPase, Rab5a is a crucial regulatory component of the endocytic pathway. Activation of Rab5a is mediated by GDP-GTP exchange factors (GEFs) that generate the Rab5-GTP complex.
• Sequences of amino acids: MASRGATRPN GPNTGNKICQ FKLVLLGESA VGKSSLVLRF VKGQFHEFQE STIGAAFLTQ TVCLDDTTVK FEIWDTAGQE RYHSLAPMYY RGAQAAIVVY DITNEESFAR AKNWVKELQR QASPNIVIAL SGNKADLANK RAVDFQEAQS YADDNSLLFM ETSAKTSMNV NEIFMAIAKK LPKNEPQNPG ANSARGRGVD LTEPTQPTRN QCCSN
• Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0)
• Purity: > 95% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Endotoxin Level: < 1.0 EU per 1ug of protein (determined by LAL method)
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RAB5A RAB5A, member RAS oncogene family [ Homo sapiens ]
• Synonyms: RAB5A; RAB5A, member RAS oncogene family; RAB5; RAS-associated protein RAB5A
• Gene ID: 5856
• mRNA Refseq: NM_004162
• Protein Refseq: NP_004153
• MIM: 179512
• UniProt ID: P20339
• Chromosome Location: 3p24-p22
• Pathway: Amyotrophic lateral sclerosis (ALS)
• Function: GTP binding; GTPase activity; guanyl nucleotide binding; nucleotide binding; protein binding