"VDAC1" Related Products


Recombinant Human VDAC1, His-tagged

Cat.No.: VDAC1-19H
Product Overview: Recombinant Human VDAC1, fused with N-terminal 6*HIS, was expressed in E. coli.
Description: This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.
Source: E. coli
Species: Human
Tag: His
Form: Protein lyophilized in sterile PBS (58 mM Na2HPO4, 17 mM NaH2PO4, 68 mM NaCl, 300 mM Imidazole, pH 8.0). Trehalose (5-8%) and mannitol (5-8%) protectants were added before lyophilization.
Bio-activity: Not tested
Endotoxin: Please contact the lab for more information.
Purity: > 90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
Stability: Store for up to 12 months at -20°C to -80°C as lyophilized powder.
Storage: Short-term storage: Store at 2-8°C for two weeks.Long-term storage: Aliquot and store at -20°C to -80°C for up to 6 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Reconstitution: Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage (see Stability and Storage for more details).If a different concentration is needed for your purposes please adjust the reconstitution volume as required (please note: the ion concentration of the final solution will vary according to the volume used).Note: Centrifuge vial before opening. When reconstituting, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature (see below).
Gene Name: VDAC1 voltage-dependent anion channel 1 [ Homo sapiens (human) ]
Official Symbol: VDAC1
Synonyms: VDAC1; voltage-dependent anion channel 1; PORIN; VDAC-1; voltage-dependent anion-selective channel protein 1; porin 31HL; porin 31HM; plasmalemmal porin; outer mitochondrial membrane protein porin 1
Gene ID: 7416
mRNA Refseq: NM_003374
Protein Refseq: NP_003365
MIM: 604492
UniProt ID: P21796
Chromosome Location: 5q31
Pathway: Calcium signaling pathway; HTLV-I infection; Huntington's disease; Metabolism of proteins
Function: porin activity; protein kinase binding; voltage-gated anion channel activity

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