Recombinant Human XIAP Protein, MYC/DDK-tagged
Cat.No. : | XIAP-399H |
Product Overview : | Recombinant protein of human X-linked inhibitor of apoptosis (XIAP) with C-MYC/DDK tag was expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11. |
Source : | HEK293T |
Species : | Human |
Tag : | MYC/DDK |
Molecular Mass : | 56.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at –80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | XIAP |
Official Symbol : | XIAP X-linked inhibitor of apoptosis [ Homo sapiens (human) ] |
Synonyms : | XIAP; X-linked inhibitor of apoptosis; API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3; E3 ubiquitin-protein ligase XIAP; IAP-like protein; RING-type E3 ubiquitin transferase XIAP; X-linked IAP; X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase; baculoviral IAP repeat-containing protein 4; inhibitor of apoptosis protein 3; EC 2.3.2.27 |
Gene ID : | 331 |
mRNA Refseq : | NM_001167.3 |
Protein Refseq : | NP_001158.2 |
MIM : | 300079 |
UniProt ID : | P98170 |
Products Types
◆ Recombinant Protein | ||
XIAP-2873H | Recombinant Human Full length XIAP protein(1-497 aa), C-His-tagged | +Inquiry |
XIAP-6266R | Recombinant Rat XIAP Protein, His (Fc)-Avi-tagged | +Inquiry |
XIAP-0712H | Recombinant Human XIAP Protein (Y120-P260), GST tagged | +Inquiry |
XIAP-10221M | Recombinant Mouse XIAP Protein, His (Fc)-Avi-tagged | +Inquiry |
XIAP-2812H | Recombinant Human XIAP protein(351-430 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
XIAP-263HCL | Recombinant Human XIAP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket