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Recombinant Human ubiquitin B

Cat. No. : UBB-28H
Product Overview : Recombinant human Ubiquitin(76amino acid) was overexpressed in E.coli and purified by using conventional chromatography techniques.
Description : Ubiquitin is a small protein that is composed of 76 amino acids and its sequence is highly conserved throughout evolution from invertebrates to mammals. In the cytoplasm, ubiquitin is involved in ATP-dependent nonlysomal proteolysis of various proteins. In the nucleus, ubiquitin is conjugated to histone2A and may play a role in regulation of chromatin structure and/or regulation of transcriptional activity.
Source : Escherichia Coli.
Form : Liquid. In 50 mM HEPES buffer (pH 7.5) containing 150 mM NaCl 10% glycerol
Purity : > 95% by SDS - PAGE.
Concentration : 1 mg/ml (determined by Bradford assay)
Sequences of amino acids : MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN IQKESTLHLV LRLRGG
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Parkinson"s disease; Apoptosis; Cell Cycle Checkpoints; Cell Cycle, Mitotic; DNA Replication; HIV Infection; Signaling by EGFR; Signaling by Wnt; Signaling in Immune system; Signalling by NGF
Gene Name : UBB ubiquitin B [ Homo sapiens ]
Synonyms : FLJ25987; MGC8385; OTTHUMP00000064960; OTTHUMP00000064961; UBA80; UBCEP1; UBCEP2; polyubiquitin B; ubiquitin B; UBB; polyubiquitin B.
Gene ID : 7314
mRNA Refseq : NM_018955
Protein Refseq : NP_061828
MIM : 191339
UniProt ID : P62988
Chromosome Location : 17p12-p11.2
Function : protein binding; transcription regulator activity

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