Recombinant Human LIPC, His-tagged LIPC-267H

Recombinant Human LIPC, His-tagged

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Recombinant Human LIPC, His-tagged

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Cat.No. : LIPC-267H
Product Overview : Recombinant Human LIPC(Gln25~Gly247), fused with N-terminal His-Tag, was expressed in E.coli.
Description : LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake.
Source : E.coli
Species : Human
Tag : His
Form : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Molecular Mass : 26.0kDa
AA Sequence : The target protein is fused with N-terminal His-Tag, its sequence is listed below.MGHHHHHHSG SEF- QSLKPE PFGRRAQAVE TNKTLHEMKT RFLLFGETNQ GCQIRINHPD TLQECGFNSS LPLVMIIHGW SVDGVLENWI WQMVAALKSQ PAQPVNVGLV DWITLAHDHY TIAVRNTRLV GKEVAALLRW LEESVQLSRS HVHLIGYSLG AHVSGFAGSS IGGTHKIGRI TGLDAAGPLF EGSAPSNRLS PDDANFVDAI HTFTREHMGL SVGIKQPIGH YDFYPNG
Endotoxin : <1.0 EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : LIPC lipase, hepatic [ Homo sapiens (human) ]
Official Symbol : LIPC
Synonyms : LIPC; lipase, hepatic; HL; HTGL; LIPH; HDLCQ12; hepatic triacylglycerol lipase; hepatic lipase; lipase member C; NP_000227.2; EC 3.1.1.3
Gene ID : 3990
mRNA Refseq : NM_000236
Protein Refseq : NP_000227
MIM : 151670
UniProt ID : P11150
Chromosome Location : 15q21-q23
Pathway : Acylglycerol degradation; Fatty Acid Beta Oxidation; Lipoprotein metabolism
Function : apolipoprotein binding; low-density lipoprotein particle binding; triglyceride lipase activity

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