Recombinant Human MYH9, GST-tagged
Cat.No. : | MYH9-29H |
Product Overview : | Recombinant Human MYH9(131 a.a. - 220 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 35.64 kDa |
AA Sequence : | RLKQLKRQLEEAEEEAQRANASRRK LQRELEDATETADAMNREVSSLKNK LRRGDLPFVVPRRMARKGAGDGSDE EVDGKADGAEAKPAE |
Applications : | ELISA; WB-Re; AP; Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MYH9 myosin, heavy chain 9, non-muscle [ Homo sapiens (human) ] |
Official Symbol : | MYH9 |
Synonyms : | MYH9; myosin, heavy chain 9, non-muscle; DFNA17, myosin, heavy polypeptide 9, non muscle; myosin-9; EPSTS; FTNS; MHA; NMHC II A; NMMHCA; nonmuscle myosin heavy chain II A |
Gene ID : | 4627 |
mRNA Refseq : | NM_002473 |
Protein Refseq : | NP_002464 |
MIM : | 160775 |
UniProt ID : | P35579 |
Chromosome Location : | 22q13.1 |
Pathway : | Axon guidance; Developmental Biology; EPHA-mediated growth cone collapse; Regulation of actin cytoskeleton |
Function : | ADP binding; contributes_to actin filament binding; contributes_to actin-dependent ATPase activity |
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Myh9-5950R | Recombinant Rat Myh9 protein, His&Myc-tagged | +Inquiry |
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MYH9-7026C | Recombinant Chicken MYH9 | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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