"HSP90AB1" Related Products

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Recombinant Human HSP90AB1, His-tagged

Cat.No.: HSP90AB1-49H
Product Overview: Recombinant Human HSP90AB1(Met1~Asp724), fused with N-terminal His-Tag, was expressed in E.coli.
Description: This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes.
Source: E.coli
Species: Human
Tag: His
Form: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Molecular Mass: 85.5kDa
AA Sequence: The target protein is fused with N-terminal His-Tag, its sequence is listed below.MGHHHHHHSGSEFELRRQ-MPEEVHHGEE EVETFAFQAE IAQLMSLIIN TFYSNKEIFL RELISNASDA LDKIRYESLT DPSKLDSGKE LKIDIIPNPQ ERTLTLVDTG IGMTKADLIN NLGTIAKSGT KAFMEALQAG ADISMIGQFG VGFYSAYLVA EKVVVITKHN DDEQYAWESS AGGSFTVRAD HGEPIGRGTK VILHLKEDQT EYLEERRVKE VVKKHSQFIG YPITLYLEKE REKEISDDEA EEEKGEKEEE DKDDEEKPKI EDVGSDEEDD SGKDKKKKTK KIKEKYIDQE ELNKTKPIWT RNPDDITQEEYGEFYKSLTN DWEDHLAVKH FSVEGQLEFR ALLFIPRRAP FDLFENKKKK NNIKLYVRRV FIMDSCDELI PEYLNFIRGV VDSEDLPLNI SREMLQQSKI LKVIRKNIVK KCLELFSELA EDKENYKKFY EAFSKNLKLG IHEDSTNRRR LSELLRYHTS QSGDEMTSLS EYVSRMKETQ KSIYYITGES KEQVANSAFV ERVRKRGFEV VYMTEPIDEY CVQQLKEFDG KSLVSVTKEG LELPEDEEEK KKMEESKAKF ENLCKLMKEI LDKKVEKVTI SNRLVSSPCC IVTSTYGWTA NMERIMKAQA LRDNSTMGYM MAKKHLEINP DHPIVETLRQ KAEADKNDKA VKDLVVLLFE TALLSSGFSL EDPQTHSNRI YRMIKLGLGI DEDEVAAEEP NAAVPDEIPP LEGDEDASRM EEVD
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: > 95%
Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months.
Gene Name: HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 [ Homo sapiens (human) ]
Official Symbol: HSP90AB1
Synonyms: HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1; HSPC2; HSPCB; D6S182; HSP90B; FLJ26984; HSP90-BETA; heat shock 90kDa protein 1, beta; OTTHUMP00000016518; OTTHUMP00000016519; heat shock protein beta; Heat shock protein HSP 90-beta; HSP 90; HSP 84; OTTHUMP00000016517; OTTHUMP00000039869; heat shock 90kD protein 1, beta
Gene ID: 3326
mRNA Refseq: NM_007355
Protein Refseq: NP_031381
MIM: 140572
UniProt ID: P08238
Chromosome Location: 6p12
Pathway: Antigen processing and presentation; NOD-like receptor signaling pathway; Pathways in cancer; Progesterone-mediated oocyte maturation; Prostate cancer
Function: ATP binding; TPR domain binding; nitric-oxide synthase regulator activity; nucleotide binding; unfolded protein binding

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