"CTH" Related Products


Recombinant Human CTH, MYC/DDK-tagged

Cat.No.: CTH-1335H
Product Overview: Recombinant Human CTH, transcript variant 1, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.
Description: This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.
Source: HEK293 cells
Species: Human
Molecular Mass: 44.3 kDa
Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name: CTH cystathionine gamma-lyase [ Homo sapiens (human) ]
Official Symbol: CTH
Synonyms: CTH; cystathionase (cystathionine gamma-lyase); MGC9471; cystathionine gamma-lyase; OTTHUMP00000010945; OTTHUMP00000010946; gamma-cystathionase; homoserine deaminase; cysteine desulfhydrase; homoserine dehydratase; EC
Gene ID: 1491
mRNA Refseq: NM_001902
Protein Refseq: NP_001893
MIM: 607657
UniProt ID: P32929
Chromosome Location: 1p31.1
Pathway: Cysteine and methionine metabolism; Glycine; L-cysteine degradation II; Metabolic pathways; Nitrogen metabolism; Selenium Pathway; Selenocompound metabolism;
Function: L-cysteine desulfhydrase activity; cystathionine beta-lyase activity; cystathionine gamma-lyase activity; lyase activity; pyridoxal phosphate binding

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