Recombinant Human CD58, Fc-tagged therapeutic protein
Cat.No. : | CD58-P058H |
Product Overview : | Immunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of human IgG1. Produced by CHO cells, mW is 91.4 kD. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. |
Source : | CHO |
Species : | Human |
Tag : | Fc |
Molecular Mass : | 91.4 kD |
AA Sequence : | >heavy chainCFSQQIYGVVYGNVTFHVPS NVPLKEVLWKKQKDKVAELENSEFR AFSSFKNRVYLDTVSGSLTIYNLTS SDEDEYEMESPNITDTMKFFLYVLE SLPSPTLTCALTNGSIEVQCMIPEH YNSHRGLIMYSWDCPMEQCKRNSTS IYFKMENDLPQKIQCTLSNPLFNTT SSIILTTCIPSSGHSRHRYALIPIP LAVITTCIVLYMNGILKCDRKPDRT NSNRVEPKSCDKTHTCPPCPAPELL GGPSVFLFPPKPKDTLMISRTPEVT CVVVDVSHEDPQVKFNWYVDGVQVH NAKTKPREQQYNSTYRVVSVLTVLH QNWLDGKEYKCKVSNKALPAPIEKT ISKAKGQPREPQVYTLPPSREEMTK NQVSLTCLVKGFYPSDIAVEWESNG QPENNYKTTPPVLDSDGSFFLYSKL TVDKSRWQQGNVFSCSVMHEALHNH YTQKSLSLSPGK>light chainMVAGSDAGRALGVLSVVCLL HCFGFISCFSQQIYGVVYGNVTFHV PSNVPLKEVLWKKQKDKVAELENSE FR AFSSFKNRVYLDTVSGSLTIYNLTS SDEDEYEMESPNITDTMKFFLYVLE SLPSPTLTCALTNGSIEVQCMIPEH YNSHRGLIMYSWDCPMEQCKRNSTS IYFKMENDLPQKIQCTLSNPLFNTT SSIILTTCIPSSGHSRHRYALIPIP LAVITTCIVLYMNGILKCDRKPDRT NSN |
Endotoxin : | < 1.0 EU per μg of the protein |
Purity : | >95% |
Storage : | Can be stored at +4 centigrade short term (1-2weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoidrepeated freezing and thawing cycles. |
Gene Name : | CD58 CD58 molecule [ Homo sapiens ] |
Official Symbol : | CD58 |
Synonyms : | CD58; CD58 molecule; CD58 antigen, (lymphocyte function associated antigen 3) , LFA3; lymphocyte function-associated antigen 3; surface glycoprotein LFA-3; CD58 antigen, (lymphocyte function-associated antigen 3); ag3; LFA3; LFA-3; FLJ23181; FLJ43722; |
Gene ID : | 965 |
mRNA Refseq : | NM_001144822 |
Protein Refseq : | NP_001138294 |
MIM : | 153420 |
UniProt ID : | P19256 |
Chromosome Location : | 1p13 |
Pathway : | Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
CD58-201H | Recombinant Human CD58 Protein, His-tagged | +Inquiry |
CD58-165H | Recombinant Human CD58 Protein, His-tagged | +Inquiry |
CD58-246H | Recombinant Human CD58 Protein, His-tagged | +Inquiry |
CD58-166H | Recombinant Human CD58 Protein, Fc-tagged | +Inquiry |
CD58-571R | Recombinant Rhesus Macaque CD58 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CD58-797CCL | Recombinant Cynomolgus CD58 cell lysate | +Inquiry |
CD58-1127HCL | Recombinant Human CD58 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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