Recombinant Human Cytochrome P450 17A1

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Recombinant Human Cytochrome P450 17A1

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Cat.No. : CYP17A1-01H
Source : E.coli
Species : Human
Form : 50mM Tris- HCl, pH7.4, 200mM NaCl, 10% glycerol
Molecular Mass : Theoretical MW: ~55kDa
AA Sequence : AKKTGAKYPK SLLSLPLVGS LPFLPRHGHM HNNFFKLQKK YGPIYSVRMG TKTTVIVGHH QLAKEVLIKK GKDFSGRPQM ATLDIASNNR KGIAFADSGA HWQLHRRLAM ATFALFKDGD QKLEKIICQE ISTLCDMLAT HNGQSIDISF PVFVAVTNVI SLICFNTSYK NGDPELNVIQ NYNEGIIDNL SKDSLVDLVP WLKIFPNKTL EKLKSHVKIR NDLLNKILEN YKEKFRSDSI TNMLDTLMQA KMNSDNGNAG PDQDSELLSD NHILTTIGDI FGAGVETTTS VVKWTLAFLL HNPQVKKKLY EEIDQNVGFS RTPTISDRNR LLLLEATIRE VLRLRPVAPM LIPHKANVDS SIGEFAVDKG TEVIINLWAL HHNEKEWHQP DQFMPERFLN PAGTQLISPS VSYLPFGAGP RSCIGEILAR QELFLIMAWL LQRFDLEVPD DGQLPSLEGI PKVVFLIDSF KVKIKVRQAW REAQAEGST
Purity : >90% determined by SDS-PAGE.
Storage : Short Term Storage +4°C. Long Term Storage -20°C please prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Gene Name : CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 [ Homo sapiens ]
Official Symbol : CYP17A1
Synonyms : CYP17A1; cytochrome P450, family 17, subfamily A, polypeptide 1; CYP17, cytochrome P450, subfamily XVII (steroid 17 alpha hydroxylase), adrenal hyperplasia; steroid 17-alpha-hydroxylase/17,20 lyase; CPT7; P450C17; S17AH; Steroid 17 alpha monooxygenase; CYPXVII; cytochrome P450c17; cytochrome P450-C17; cytochrome P450 17A1; cytochrome p450 XVIIA1; steroid 17-alpha-monooxygenase; cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia; CYP17;
Gene ID : 1586
mRNA Refseq : NM_000102
Protein Refseq : NP_000093
MIM : 609300
UniProt ID : P05093
Chromosome Location : 10q24.3
Pathway : Androgen biosynthesis, organism-specific biosystem; Biological oxidations, organism-specific biosystem; C19/C18-Steroid hormone biosynthesis, pregnenolone =>androstenedione => estrone, organism-specific biosystem; C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione =>
Function : electron carrier activity; heme binding; metal ion binding; monooxygenase activity; oxygen binding; steroid 17-alpha-monooxygenase activity;

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Related Gene

CYP2C19CYP2C9CYP2D6CYP2E1CYP3A4CYP1B1CYP24A1CYP2J2CYP46A1CYP7B1CYP1A2CYP19A1CYP26A1CYP26B1CYP2A6CYP3A5CYP3A7CYP4F11CYP4F3CYP7A1CYP2C6CYP3A23/3A1CYP1A1CYP2B6CYP4A11Cyp11a1CYP2C8CYP2D4CYP3A2CYP2C18CYP3A43CYP4B1CYP2U1CYP2W1CYP39A1CYP2D1CYP2R1CYP26C1CYP27A1CYP2S1CYP2C11CYP4V2CYP4X1CYP4Z1CYP11B1CYP19A1BCYP4F12CYP4F2CYP4F22CYP38CYP27B1CYP27C1CYP2A13CYP2A7CYP20A1CYP21A2CYP4F8CYP17A1CYP2C23CYP4A22CYP4F13Cyp2a1Cyp2a12Cyp2b3Cyp2b9Cyp2c12Cyp2c13Cyp2c22Cyp2c29Cyp2c38Cyp2c39Cyp2c40Cyp2c44Cyp2c50Cyp2c54Cyp2d11Cyp2d12Cyp2d2Cyp2d22Cyp2d26Cyp2d3Cyp2d34Cyp2d40Cyp2d5Cyp2d9Cyp2f2Cyp2f4Cyp2g1Cyp2c37Cyp21a1Cyp3a11Cyp3a13Cyp3a16Cyp3a18Cyp3a25Cyp3a41aCyp3a41bCyp3a57Cyp4a31Cyp4a32Cyp4a8Cyp4f1Cyp4f14Cyp4f15Cyp4f17Cyp4f18Cyp4f6Cyp4v3Cyp51CYP8B1Cyp11b2Cyp11b3Cyp2a2Cyp2a22Cyp2a3Cyp2a4Cyp2a5Cyp2ab1Cyp2b1Cyp2b10Cyp2b12Cyp2b13Cyp2b15Cyp2b19Cyp2b21Cyp2b23Cyp2c6v1Cyp2c65Cyp2c66Cyp2c67Cyp2c68Cyp2c69Cyp2c7CYP2F1Cyp2j10Cyp2j12Cyp2j13Cyp2j4Cyp2j8Cyp2j9Cyp2t1Cyp2t4Cyp3a23Cyp3a44Cyp3a62Cyp3a9Cyp4a1Cyp4a12aCyp4a12bCyp4a14Cyp4a2Cyp4a29Cyp4a3Cyp4a30bCyp4f39Cyp4f4Cyp4f40Cyp4f5CYP51A1Cyp3a59CYP1B1-AS1CYP2B7P1

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