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Recombinant Mouse Tfrc, Fc-tagged

Cat.No.: Tfrc-01M
Product Overview: Recombinant mouse mature form TFRC (Q62351) (Cys 89 - Phe 763 ) extracellular domain was fused with a Fc tag at the C-terminus was expressed in HEK293.
Description: This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis.
Source: HEK293
Species: Mouse
Tag: Fc
Form: 50 mM Tris-HCl, pH 7.4, 100mM NaCl2, and 5% Trehalose
Molecular Mass: ~100 kDa
Purity: >90% as determined by SDS-PAGE
Storage Buffer: This lyophilized preparation is stable at 4°C, but should be kept at -20°C for long term storage. Upon reconstitution, the preparation is stable for up to 2 weeks at 4°C. For maximal stability, apportion the reconstituted preparation into sterile distilled water or working aliquots with 20% glycerol or 0.1% BSA and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Gene Name: Tfrc transferrin receptor [ Mus musculus ]
Official Symbol: Tfrc
Synonyms: TFRC; transferrin receptor; transferrin receptor protein 1; mammary tumor virus receptor 1; TR; TFR; p90; CD71; TFR1; Trfr; Mtvr1; Mtvr-1; AI195355; AI426448; AU015758; 2610028K12Rik; E430033M20Rik;
Gene ID: 22042
mRNA Refseq: NM_011638
Protein Refseq: NP_035768
UniProt ID: Q62351
Chromosome Location: 16 B3; 16 23.06 cM
Pathway: Clathrin derived vesicle budding, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Membrane Trafficking, organism-specific biosystem;
Function: Hsp70 protein binding; chaperone binding; iron ion transmembrane transporter activity; peptidase activity; receptor activity; transferrin receptor activity; transferrin receptor activity;

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