Recombinant Human BPI, Fc Chimera BPI-175H

Recombinant Human BPI, Fc Chimera

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Recombinant Human BPI, Fc Chimera

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Cat.No. : BPI-175H
Product Overview : Recombinant Human BPI (Accession # AAA51841) was produced in Human embryonic kidney cell, HEK293-derived.
Source : HEK293 cells
Species : Human
Tag : Fc Chimera
Predicted N Terminal : Val32
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its ability to inhibit LPS-induced IL-8 secretion by THP-1 human acute monocytic leukemia cells. Wilde, C.G. et al. (1994) J. Biol. Chem. 269:17411.The ED50 for this effect is typically 0.4-2.4 ng/mL.
Molecular Mass : Recombinant Human BPI, Fc Chimera has a calculated MW of 77.3 kDa (monomer). In SDS-PAGE migrates as 75-85 kDa, reducing conditions.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : BPI bactericidal/permeability-increasing protein [ Homo sapiens ]
Official Symbol : BPI
Synonyms : BPI; bactericidal/permeability-increasing protein; bactericidal permeability-increasing protein; BPI fold containing family D; member 1; BPIFD1; CAP 57; recombinant BPI holoprotein, rBPI; BPI fold containing family D, member 1; rBPI;
Gene ID : 671
mRNA Refseq : NM_001725
Protein Refseq : NP_001716
MIM : 109195
UniProt ID : P17213
Chromosome Location : 20q11.23

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