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Recombinant Human JAG2, Fc Chimera

Cat.No.: JAG2-229H
Product Overview: Recombinant Human JAG2 (Accession # AAB84215) was produced in Chinese Hamster Ovary cell line, CHO-derived.
Source: CHO cells
Species: Human
Tag: Fc Chimera
Predicted N Terminal: Met27
Form: Lyophilized from a 0.2 µm filtered solution in PBS and EDTA.
Bio-activity: Measured by the ability of the immobilized protein to enhance BMP-2 induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. Nobta, M. et al. (2005) J. Biol. Chem. 280:15842.The ED50 for this effect is typically 0.5-2 µg/mL.
Molecular Mass: Recombinant Human JAG2, Fc Chimera has a calculated MW of 138.7 kDa (monomer). In SDS-PAGE migrates as 165-175 kDa, reducing conditions.
Purity: >85%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name: JAG2 jagged 2 [ Homo sapiens ]
Official Symbol: JAG2
Synonyms: JAG2; jagged 2; protein jagged-2; HJ2; SER2;
Gene ID: 3714
mRNA Refseq: NM_002226
Protein Refseq: NP_002217
MIM: 602570
UniProt ID: Q9Y219
Chromosome Location: 14q32

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