"KDR" Related Products

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Recombinant Human KDR, Fc Chimera

Cat.No.: KDR-236H
Product Overview: Recombinant Human KDR (Accession # AAC16450) was produced in Mouse myeloma cell line, NS0-derived.
Source: NSO cells
Species: Human
Tag: Fc Chimera
Predicted N Terminal: Ala20
Form: Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity: Measured by its ability to inhibit the VEGF-dependent proliferation of HUVEC human umbilical vein endothelial cells.The ED50 for this effect is typically 10-40 ng/mL in the presence of 5 ng/mL rhVEGF165.
Molecular Mass: Recombinant Human KDR, Fc Chimera has a calculated MW of 110 kDa (monomer). In SDS-PAGE migrates as 160-170 kDa, reducing conditions.
Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution: Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name: KDR kinase insert domain receptor (a type III receptor tyrosine kinase) [ Homo sapiens ]
Official Symbol: KDR
Synonyms: KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR; VEGFR2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor;
Gene ID: 3791
mRNA Refseq: NM_002253
Protein Refseq: NP_002244
MIM: 191306
UniProt ID: P35968
Chromosome Location: 4q11-q12

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