Recombinant Human KDR, Fc Chimera KDR-236H

Recombinant Human KDR, Fc Chimera

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Recombinant Human KDR, Fc Chimera

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Cat.No. : KDR-236H
Product Overview : Recombinant Human KDR (Accession # AAC16450) was produced in Mouse myeloma cell line, NS0-derived.
Source : NSO cells
Species : Human
Tag : Fc Chimera
Predicted N Terminal : Ala20
Form : Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity : Measured by its ability to inhibit the VEGF-dependent proliferation of HUVEC human umbilical vein endothelial cells.The ED50 for this effect is typically 10-40 ng/mL in the presence of 5 ng/mL rhVEGF165.
Molecular Mass : Recombinant Human KDR, Fc Chimera has a calculated MW of 110 kDa (monomer). In SDS-PAGE migrates as 160-170 kDa, reducing conditions.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : KDR kinase insert domain receptor (a type III receptor tyrosine kinase) [ Homo sapiens ]
Official Symbol : KDR
Synonyms : KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR; VEGFR2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor;
Gene ID : 3791
mRNA Refseq : NM_002253
Protein Refseq : NP_002244
MIM : 191306
UniProt ID : P35968
Chromosome Location : 4q11-q12

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