"GFRA3" Related Products


Recombinant Human GFRA3, Fc Chimera

Cat.No.: GFRA3-237H
Product Overview: Recombinant Human GFRA3 (Accession # AAC24355) was produced in Spodoptera frugiperda, Sf 21 (baculovirus)-derived.
Source: Baculovirus Sf 21 Insect cells
Species: Human
Tag: Fc Chimera
Predicted N Terminal: Gly31 & Asp32
Form: Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity: Binding of R&D Systems" human GFR alpha -3/Fc Chimera to immobilized Artemin has been reported. Baloh, R. et al. (1998) Neuron 21:1291.80 ng/mL of the rhMSP significantly induces phosphorylation of MSP R/Ron measured by DuoSet IC human phospho-MSP R/Ron kit. Measured by its binding ability in a functional ELISA.Immobilized Recombinant Human Artemin at 1 µg/mL can bind Recombinant Human GFR alpha -3/GDNF R alpha -3 Fc Chimera with an apparent Kd <1 nM.
Molecular Mass: Recombinant Human GFRA3, Fc Chimera has a calculated MW of 67 kDa (monomer). In SDS-PAGE migrates as 67 kDa, reducing conditions.
Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name: GFRA3 GDNF family receptor alpha 3 [ Homo sapiens ]
Official Symbol: GFRA3
Synonyms: GFRA3; GDNF family receptor alpha 3; GDNF family receptor alpha-3; GFRa 3; GFR-alpha-3; GDNFR-alpha-3; GPI-linked receptor; GDNF receptor alpha-3; glial cell line-derived neurotrophic factor receptor alpha-3;
Gene ID: 2676
mRNA Refseq: NM_001496
Protein Refseq: NP_001487
MIM: 605710
UniProt ID: O60609
Chromosome Location: 5q31.1-q31.3

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