Recombinant Human TNFSF11, Met-tagged TNFSF11-252H

Recombinant Human TNFSF11, Met-tagged

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Recombinant Human TNFSF11, Met-tagged

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Cat.No. : TNFSF11-252H
Product Overview : Recombinant Human TNFSF11 (Accession # AAC51762) Arg85-Asp245, fused with an N-terminal Met, was produced in E. coli-derived.
Source : E. coli
Species : Human
Predicted N Terminal : Met
Form : Lyophilized from a 0.2 µm filtered solution in MES and NaCl with BSA as a carrier protein.
Bio-activity : Measured by its ability to induce osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells.The ED50 for this effect is typically 2-12 ng/mL.
Molecular Mass : Recombinant Human TNFSF11, Met-tagged has a calculated MW of 18.3 kDa. In SDS-PAGE migrates as 19 kDa, reducing conditons.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 [ Homo sapiens ]
Official Symbol : TNFSF11
Synonyms : TNFSF11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand superfamily member 11; CD254; ODF; OPGL; RANKL; TRANCE; osteoprotegerin ligand; osteoclast differentiation factor; TNF-related activation-induced cytokine; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; sOdf; OPTB2; hRANKL2;
Gene ID : 8600
mRNA Refseq : NM_003701
Protein Refseq : NP_003692
MIM : 602642
UniProt ID : O14788
Chromosome Location : 13q14

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