Recombinant Human BCL2L1 protein, His-tagged BCL2L1-511H

Recombinant Human BCL2L1 protein, His-tagged

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Recombinant Human BCL2L1 protein, His-tagged

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Cat.No. : BCL2L1-511H
Product Overview : Recombinant Human BCL2L1 (Met1-Arg212) protein was fused to His-tag at C-terminus and expressed in E.coli.
Description : Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1/Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1/Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
Source : E.coli
Species : Human
Tag : His
Predicted N Terminal : Met1
Form : Lyophilized from 0.22 μm filtered solution in 20 mM HEPES, 50 mM KCl, pH7.5, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 24.6 kDa. The protein migrates as 26-28 kDa under reducing (R) condition (SDS-PAGE).
Protein length : Met1-Arg212
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >92% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
SDS-PAGE of BCL2L1-511H :

Human Bcl-x, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%.

Gene Name : BCL2L1
Official Symbol : BCL2L1
Synonyms : BCL2L1; BCL2-like 1; bcl-2-like protein 1; Bcl X; bcl xL; bcl xS; BCL2L; BCLX; PPP1R52; protein phosphatase 1; regulatory subunit 52; apoptosis regulator Bcl-X; protein phosphatase 1, regulatory subunit 52; BCLXL; BCLXS; Bcl-X; bcl-xL; bcl-xS; BCL-XL/S; DKFZp781P2092
Gene ID : 598
mRNA Refseq : NM_001191
Protein Refseq : NP_001182
MIM : 600039
UniProt ID : Q07817

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