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Active Recombinant Human SUMO1

Cat.No. : SUMO1-565H
Product Overview : Recombinant Human SUMO1 (Accession # NM_003352) was produced in E. coli-derived.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Human
Form : Supplied as a solution in HEPES, NaCl and DTT
Bio-activity : SUMO1 chains do not readily form in vitro . However, the role of SUMO1 in poly-SUMO chain formation is an area of intense research. Utilizing Recombinant Human SUMO1 Mutant K17R will ensure that K17-linked chains will not be formed. Reaction conditions will need to be optimized for each specific application. We recommend an initial Recombinant Human SUMO1 Mutant K17R concentration of 10-50 µM.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) [ Homo sapiens ]
Official Symbol : SUMO1
Synonyms : SUMO1; SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae); SMT3 suppressor of mif two 3 homolog 1 (yeast) , ubiquitin like 1 (sentrin) , UBL1; small ubiquitin-related modifier 1; GMP1; OFC10; PIC1; SMT3C; SMT3H3; SUMO 1; sentrin; SMT3 homolog 3; GAP modifying protein 1; ubiquitin-like protein UBL1; ubiquitin-like protein SMT3C; ubiquitin-homology domain protein PIC1; DAP1; SMT3; UBL1; SENP2;
Gene ID : 7341
mRNA Refseq : NM_001005781
Protein Refseq : NP_001005781
MIM : 601912
UniProt ID : P63165
Chromosome Location : 2q33

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How do alterations in SUMO1 expression or conjugation affect cancer development and progression? 04/06/2022

Changes in SUMO1 expression or activity can contribute to cancer development, affecting tumor cell behavior and environment.

How does SUMO1 modification affect the stability and function of target proteins? 12/22/2021

SUMO1 modification alters target protein stability and function, affecting various cellular processes.

What role does SUMO1 play in regulating gene expression and chromatin organization? 12/14/2021

SUMO1 regulates gene expression and chromatin structure, influencing transcriptional activity.

How does SUMO1 influence the DNA damage response and repair processes? 11/09/2020

SUMO1 is involved in the DNA damage response, aiding in DNA repair and maintaining genomic integrity.

What is the impact of SUMO1 on cellular stress responses, particularly in neurodegenerative diseases? 07/19/2020

SUMO1 impacts cellular stress responses, playing a significant role in neurodegenerative disease mechanisms.

How does SUMO1 contribute to the regulation of cell cycle progression and apoptosis? 11/28/2019

SUMO1 modulates cell cycle progression and apoptosis, contributing to cell survival and turnover.

What are the mechanisms by which SUMO1 modulates signal transduction pathways, especially in immune responses? 02/01/2019

SUMO1 influences signal transduction, particularly in immune cell signaling and response.

Customer Reviews (3)

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Reviews
05/07/2022

    Swift protein expression optimization, boosts our research efficiency.

    11/30/2021

      Accurate protein structural characterization, vital for our studies.

      02/03/2018

        High-quality protein sequencing, invaluable for our work.

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