| Cat.No.: | ITGA6&ITGB1-608H |
| Product Overview: | Recombinant Human ITGA6&ITGB1 (Accession # NP_000201 ( alpha 6 subunit) & P05556 ( beta 1 subunit)) was produced in Chinese Hamster Ovary cell line, CHO-derived. |
| Source: | CHO cells |
| Species: | Human |
| Predicted N Terminal: | Phe24 ( alpha 6 subunit) & Gln21 predicted: No results obtained, sequencing might be blocked ( beta 1 subunit) |
| Form: | Lyophilized from a 0.2 µm filtered solution in PBS. |
| Bio-activity: | Measured by its binding ability in a functional ELISA.When Recombinant Human Laminin alpha 4 is coated at 5 µg/mL, Recombinant Human Integrin alpha 6 beta 1 binds with apparent KD <2nM. |
| Molecular Mass: | Recombinant Human ITGA6&ITGB1 has a calculated MW of 119 kDa ( alpha 6 subunit) & 86.4 kDa ( beta 1 subunit). In SDS-PAGE migrates as 110-140 kDa & 140 - 170 kDa, reducing conditions. |
| Purity: | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
| Storage: | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
| Gene Name: | ITGA6 integrin, alpha 6 [ Homo sapiens ] |
| Official Symbol: | ITGA6 |
| Synonyms: | ITGA6; integrin, alpha 6; integrin alpha-6; CD49f; integrin alpha6B; CD49 antigen-like family member F; VLA-6; ITGA6B; FLJ18737; DKFZp686J01244; |
| Gene ID: | 3655 |
| mRNA Refseq: | NM_000210 |
| Protein Refseq: | NP_000201 |
| MIM: | 147556 |
| UniProt ID: | P23229 |
| Chromosome Location: | 2q31.1 |
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