Active Recombinant Human ITGA6&ITGB1

• Cat.No.: ITGA6&ITGB1-608H
• Product Overview: Recombinant Human ITGA6&ITGB1 (Accession # NP_000201 ( alpha 6 subunit) & P05556 ( beta 1 subunit)) was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Source: CHO cells
• Species: Human
• Predicted N Terminal: Phe24 ( alpha 6 subunit) & Gln21 predicted: No results obtained, sequencing might be blocked ( beta 1 subunit)
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.When Recombinant Human Laminin alpha 4 is coated at 5 µg/mL, Recombinant Human Integrin alpha 6 beta 1 binds with apparent KD <2nM.
• Molecular Mass: Recombinant Human ITGA6&ITGB1 has a calculated MW of 119 kDa ( alpha 6 subunit) & 86.4 kDa ( beta 1 subunit). In SDS-PAGE migrates as 110-140 kDa & 140 - 170 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: ITGA6 integrin, alpha 6 [ Homo sapiens ]
• Official Symbol: ITGA6
• Synonyms: ITGA6; integrin, alpha 6; integrin alpha-6; CD49f; integrin alpha6B; CD49 antigen-like family member F; VLA-6; ITGA6B; FLJ18737; DKFZp686J01244
• Gene ID: 3655
• mRNA Refseq: NM_000210
• Protein Refseq: NP_000201
• MIM: 147556
• UniProt ID: P23229
• Chromosome Location: 2q31.1