Active Recombinant Human SIGLEC14, Fc Chimera

• Cat.No.: SIGLEC14-673H
• Product Overview: Recombinant Human SIGLEC14 (Accession # NP_001092082) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Fc Chimera
• Predicted N Terminal: Lys18
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of human red blood cells.The ED50 for this effect is typically 1.5 - 6 µg/mL.
• Molecular Mass: Recombinant Human SIGLEC14, Fc Chimera has a calculated MW of 64.5 kDa (monomer). In SDS-PAGE migrates as 75-80 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: SIGLEC14 sialic acid binding Ig-like lectin 14 [ Homo sapiens ]
• Official Symbol: SIGLEC14
• Synonyms: SIGLEC14; sialic acid binding Ig-like lectin 14; sialic acid-binding Ig-like lectin 14; siglec-14
• Gene ID: 100049587
• mRNA Refseq: NM_001098612
• Protein Refseq: NP_001092082
• UniProt ID: Q08ET2
• Chromosome Location: 19q13.41