Active Recombinant Human SERPINE2, His-tagged

• Cat.No.: SERPINE2-688H
• Product Overview: Recombinant Human SERPINE2 (Accession # NP_001130000) Met1-Pro397, fused with a C-terminal 10-His tag, was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: His
• Predicted N Terminal: Ser20
• Form: Supplied as a 0.2 µm filtered solution in Sodium Acetate, NaCl and Glycerol.
• Bio-activity: Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2 .The IC50 value is <2 nM, as measured under the described conditions.
• Molecular Mass: Recombinant Human SERPINE2, His-tagged has a calculated MW of 43 kDa. In SDS-PAGE migrates as 50 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 [ Homo sapiens ]
• Official Symbol: SERPINE2
• Synonyms: SERPINE2; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; PI7, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; glia-derived nexin; GDN; glial derived nexin 1; nexin; PN1; PNI; serpin E2; protease nexin I; peptidase inhibitor 7; glial-derived neurite promoting factor; PI7; PI-7; PN-1; DKFZp686A13110
• Gene ID: 5270
• mRNA Refseq: NM_001136528
• Protein Refseq: NP_001130000
• MIM: 177010
• UniProt ID: P07093
• Chromosome Location: 2q33-q35