Recombinant Human IGFBP6, Met-tagged IGFBP6-735H

Recombinant Human IGFBP6, Met-tagged

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Recombinant Human IGFBP6, Met-tagged

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Cat.No. : IGFBP6-735H
Product Overview : Recombinant Human IGFBP6 (Accession # NP_002169) Ala25-Gly240, fused with an N-terminal Met, was produced in Mouse myeloma cell line, NS0-derived.
Source : NSO cells
Species : Human
Predicted N Terminal : Met
Form : Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.
Bio-activity : Measured by its ability to inhibit the biological activity of IGF-I or IGF-II on MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083.The ED50 for this effect is typically 0.1 - 0.4 µg/mL in the presence of 14 ng/mL rhIGF-II.
Molecular Mass : Recombinant Human IGFBP6, Met-tagged has a calculated MW of 23 kDa. In SDS-PAGE migrates as 34 kDa, reducing conditions.
Purity : >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : IGFBP6 insulin-like growth factor binding protein 6 [ Homo sapiens ]
Official Symbol : IGFBP6
Synonyms : IGFBP6; insulin-like growth factor binding protein 6; insulin-like growth factor-binding protein 6; IBP-6; IGFBP-6; IGF binding protein 6; IGF-binding protein 6; IBP6;
Gene ID : 3489
mRNA Refseq : NM_002178
Protein Refseq : NP_002169
MIM : 146735
UniProt ID : P24592
Chromosome Location : 12q13

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