Active Recombinant Human INHBA&INHBC

• Cat.No.: INHBA&INHBC-737H
• Product Overview: Recombinant Human INHBA&INHBC (Accession # NP_002183 ( beta A) & NP_005529 ( beta C)) was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Source: CHO cells
• Species: Human
• Predicted N Terminal: Gly311 ( beta A subunit) & Gly237 ( beta C subunit)
• Form: Lyophilized from a 0.2 µm filtered solution in HCl with BSA as a carrier protein.
• Bio-activity: Measured by its binding ability in a functional ELISA.In a 100 µL reaction mixture containing rhActivin AC at 2 nM and rhActivin RIIB/Fc Chimera dilutions at 0.02 - 41 nM, the concentration of rhActivin RIIB/Fc Chimera that produces 50% of the optimal binding response is found to be approximately 0.8 - 4 nM.
• Molecular Mass: Recombinant Human INHBA&INHBC has a calculated MW of 12.9 kDa ( beta A subunit), 12.5 kDa ( beta C subunit). In SDS-PAGE migrates as 23 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 100 µg/mL in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: INHBA inhibin, beta A [ Homo sapiens ]
• Official Symbol: INHBA
• Synonyms: INHBA; inhibin, beta A; inhibin, beta A (activin A, activin AB alpha polypeptide); inhibin beta A chain; Inhibin, beta-1; activin beta-A chain; FSH-releasing protein; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; EDF; FRP
• Gene ID: 3624
• mRNA Refseq: NM_002192
• Protein Refseq: NP_002183
• MIM: 147290
• UniProt ID: P08476
• Chromosome Location: 7p15-p13