Active Recombinant Human ITGAV&ITGB1

• Cat.No.: ITGAV&ITGB1-740H
• Product Overview: Recombinant Human ITGAV&ITGB1 (Accession # NP_002201 (Integrin alpha V) & P05556 (Integrin beta 1)) was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Source: CHO cells
• Species: Human
• Predicted N Terminal: Phe31 ( alpha V subunit) & Gln21 ( beta 1 subunit)
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.When Recombinant Human Integrin alpha V beta 1 is coated at 5 µg/mL, Human Fibronectin binds with an apparent KD <0.1 nM.
• Molecular Mass: Recombinant Human ITGAV&ITGB1 has a calculated MW of 115.4 kDa ( alpha V subunit) & 86.4 kDa ( beta 1 subunit). In SDS-PAGE migrates as 120-170 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: ITGAV integrin, alpha V [ Homo sapiens ]
• Official Symbol: ITGAV
• Synonyms: ITGAV; integrin, alpha V; antigen identified by monoclonal L230 , integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , MSK8, vitronectin receptor , VNRA, VTNR; integrin alpha-V; CD51; integrin alphaVbeta3; vitronectin receptor subunit alpha; antigen identified by monoclonal L230; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); MSK8; VNRA; VTNR; DKFZp686A08142
• Gene ID: 3685
• mRNA Refseq: NM_001144999
• Protein Refseq: NP_001138471
• MIM: 193210
• UniProt ID: P06756
• Chromosome Location: 2q31-q32