Recombinant Human NRF1, MYC/DDK-tagged NRF1-2152H

Recombinant Human NRF1, MYC/DDK-tagged


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Recombinant Human NRF1, MYC/DDK-tagged

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Cat.No. : NRF1-2152H
Product Overview : Recombinant Human NRF1, transcript variant 2, fused with C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.
Source : HEK293 cells
Species : Human
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 53.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Usage : This product is for research and development use only. Not for use in human.
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : NRF1 nuclear respiratory factor 1 [ Homo sapiens ]
Official Symbol : NRF1
Synonyms : ALPHA-PAL; nuclear respiratory factor 1; alpha palindromic-binding protein
Gene ID : 4899
mRNA Refseq : NM_001040110
Protein Refseq : NP_001035199
MIM : 600879
UniProt ID : Q16656
Chromosome Location : 7q32
Pathway : Energy Metabolism, organism-specific biosystem; Huntington's disease, organism-specific biosystem; Metabolism, organism-specific biosystem
Function : RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; protein binding

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