"C10orf54" Related Products


Recombinant Human C10orf54, His-tagged

Cat.No.: C10orf54-837H
Product Overview: Recombinant Human C10orf54(Met1-Ala194) fussed with His tag at C-terminal was expressed in Human Cells.
Description: C10orf54, also known as GI24, belongs to the immunoglobulin superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. On ESCs, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state. On tumor cells, C10orf54 both promotes MT1-MMP expression and activity and serves as a substrate for MT1-MMP. This increases the potential for cell motility. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
Source: Human Cells
Species: Human
Tag: His
Predicted N Terminal: Phe 33
Form: Lyophilized from sterile PBS, pH 7.4
Molecular Mass: The recombinant human Gi24 consists of 173 amino acids and predicts a molecular mass of 19.6 KDa. It migrates as an approximately 38-42 KDa band in SDS-PAGE under reducing conditions.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Purity: > 95 % as determined by SDS-PAGE
Stability: Samples are stable for up to twelve months from date of receipt at -70 centigrade
Storage: Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name: C10orf54 chromosome 10 open reading frame 54 [ Homo sapiens ]
Official Symbol: C10orf54
Synonyms: B7H5; GI24; B7-H5; SISP1; PP2135; platelet receptor Gi24; sisp-1; stress induced secreted protein 1; stress-induced secreted protein-1
Gene ID: 64115
mRNA Refseq: NM_022153
Protein Refseq: NP_071436
MIM: 615608
UniProt ID: Q9H7M9
Chromosome Location: 10q22.1

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