Recombinant Human CDH3, MYC/DDK-tagged CDH3-289H

Recombinant Human CDH3, MYC/DDK-tagged

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Recombinant Human CDH3, MYC/DDK-tagged

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Cat.No. : CDH3-289H
Product Overview : Recombinant Human CDH3 fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells.
Description : This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Source : HEK293 cells
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 88.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : CDH3 cadherin 3, type 1, P-cadherin (placental) [ Homo sapiens ]
Official Symbol : CDH3
Synonyms : CDHP; HJMD; PCAD; cadherin-3; calcium-dependent adhesion protein, placental
Gene ID : 1001
mRNA Refseq : NM_001793
Protein Refseq : NP_001784
MIM : 114021
UniProt ID : P22223
Chromosome Location : 16q22.1
Pathway : Adherens junctions interactions, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem
Function : calcium ion binding; molecular_function

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