Recombinant Human CBLB, MYC/DDK-tagged

• Cat.No.: CBLB-18H
• Product Overview: Recombinant Human CBLB fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: CBL-B is an E3 ubiquitin-protein ligase that in humans is encoded by the CBLB gene. CBLB is a member of the CBL gene family.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 109.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase [ Homo sapiens ]
• Official Symbol: CBLB
• Synonyms: Cbl-b; RNF56; Nbla00127; FLJ36865, FLJ41152, DKFZp779A0729, DKFZp779F1443, DKFZp686J10223; E3 ubiquitin-protein ligase CBL-B; Cas-Br-M (murine) ecotropic retroviral transforming sequence b; Cas-Br-M (murine) ectropic retroviral transforming sequence b; Cbl proto-oncogene, E3 ubiquitin protein ligase B; RING finger protein 56; SH3-binding protein CBL-B; casitas B-lineage lymphoma proto-oncogene b; signal transduction protein CBL-B
• Gene ID: 868
• mRNA Refseq: NM_170662
• Protein Refseq: NP_733762
• MIM: 604491
• UniProt ID: Q13191
• Chromosome Location: 3q13.11
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem
• Function: calcium ion binding; ligase activity; phosphotyrosine binding