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Recombinant Human BMPR1A Protein, Fc Chimera

Cat.No.: BMPR1A-545H
Product Overview: Recombinant Human BMPR1A (Accession # NP_004320), fused with , was produced in Mouse myeloma cell line, NS0-derived.
Source: NSO Cells
Species: Human
Tag: Fc
Predicted N Terminal: Gln24 predicted: No results obtained, sequencing might be blocked
Form: Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity: Measured by its ability to inhibit rhBMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al. (1999) Exp. Cell Res. 250:351.The ED50 for this effect is typically 0.03-0.12 µg/mL in the presence of 30 ng/mL of Recombinant Human BMP-4.
Molecular Mass: Recombinant Human BMPR1A, Fc Chimera has a calculated MW of 40.8 kDa (monomer). In SDS-PAGE migrates as 59 kDa, reducing conditions.
Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name: BMPR1A bone morphogenetic protein receptor, type IA [ Homo sapiens ]
Official Symbol: BMPR1A
Synonyms: BMPR1A; bone morphogenetic protein receptor, type IA; ACVRLK3; bone morphogenetic protein receptor type-1A; ALK3; CD292; ALK-3; BMPR-1A; BMP type-1A receptor; activin receptor-like kinase 3; activin A receptor, type II-like kinase 3; serine/threonine-protein kinase receptor R5; SKR5; 10q23del;
Gene ID: 657
mRNA Refseq: NM_004329
Protein Refseq: NP_004320
MIM: 601299
UniProt ID: P36894
Chromosome Location: 10q22.3

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