"CHGA" Related Products

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Recombinant Human Chromogranin A, His-tagged

Cat. No.: CHGA -411H
Product Overview: Recombinant human Chromogranin A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography, 53.3 kDa (477aa)
Description: Chromogranin A is a member of the chromogranin/secretogranin (granins) family of neuroendocrine secretory proteins. Chromogranin A (CgA) represents the major soluble protein co-stored and co-released with catecholamines, within chromaffin cells secretory granules. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. It is considered a diagnostic and prognostic marker of several diseases, including a variety of tumours and cardiac heart failure.
Purity: > 85% by SDS - PAGE
Sequences of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMLP VNSPMNKGDT EVMKCIVEVI SDTLSKPSPM PVSQECFETL RGDERILSIL RHQNLLKELQ DLALQGAKER AHQQKKHSGF EDELSEVLEN QSSQAELKEA VEEPSSKDVM EKREDSKEAE KSGEATDGAR PQALPEPMQE SKAEGNNQAP GEEEEEEEEA TNTHPPASLP SQKYPGPQAE GDSEGLSQGL VDREKGLSAE PGWQAKREEE EEEEEEAEAG EEAVPEEEGP TVVLNPHPSL GYKEIRKGES RSEALAVDGA GKPGAEEAQD PEGKGEQEHS QQKEEEEEMA VVPQGLFRGG KSGELEQEEE RLSKEWEDSK RWSKMDQLAK ELTAEKRLEG QEEEEDNRDS SMKLSFRARA YGFRGPGPQL RRGWRPSSRE DSLEAGLPLQ VRGYPEEKKE EEGSANRRPE DQELESLSAI EAELEKVAHQ LQALRRG
Concentration: 0.5 mg/ml (determined by Bradford assay)
Form: Liquid. In 20mM MES buffer (pH 6.0) containing 2mM EDTA,0.1mM PMSF, 10% glycerol
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: CHGA chromogranin A (parathyroid secretory protein 1) [ Homo sapiens ]
Synonyms: CHGA; chromogranin A (parathyroid secretory protein 1); CGA; vasostatin; pancreastatin; parastatin;chromogranin A; parathyroid secretory protein 1; betagranin (N-terminal fragment of chromogranin A); SP-I; Pituitary secretory protein I
Gene ID: 1113
mRNA Refseq: NM_001275
Protein Refseq: NP_001266
MIM: 118910
UniProt ID: P10645
Chromosome Location: 14q32
Function: calcium ion binding

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