Recombinant Human COL18A1 COL18A1-807H

Recombinant Human COL18A1

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Recombinant Human COL18A1

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Cat.No. : COL18A1-807H
Product Overview : Recombinant Human COL18A1 (Accession # NP_569712) His1154-Ser1335, fused with an N-terminal Met and 8-His tag, was produced in E. coli.
Source : E. coli
Species : Human
Predicted N Terminal : Met-His tag
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its ability to inhibit the FGF basic-dependent proliferation of HUVEC human umbilical vein endothelial cells. Dhanabal, M. et al. (1999) Biochem. Biophys. Res. Commun. 258:345.The ED50 for this effect is typically 0.4-2 µg/mL in the presence of 20 µg/mL of Goat Anti-Human Endostatin Antigen Affinity-purified Polyclonal Antibody.
Molecular Mass : Recombinant Human COL18A1 has a calculated MW of 21.6 kDa. In SDS-PAGE migrates as 21 kDa, reducing conditions.
Protein length : His1154-Ser1335
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : COL18A1 collagen, type XVIII, alpha 1 [ Homo sapiens ]
Official Symbol : COL18A1
Synonyms : COL18A1; collagen, type XVIII, alpha 1; KNO, Knobloch syndrome, type 1; collagen alpha-1(XVIII) chain; endostatin; KNO1; KS; antiangiogenic agent; multi-functional protein MFP; KNO; FLJ27325; FLJ34914; MGC74745;
Gene ID : 80781
mRNA Refseq : NM_030582
Protein Refseq : NP_085059
MIM : 120328
UniProt ID : P39060
Chromosome Location : 21q22.3

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