Recombinant Human BMPR1B Protein, Fc Chimera BMPR1B-889H

Recombinant Human BMPR1B Protein, Fc Chimera

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Recombinant Human BMPR1B Protein, Fc Chimera

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Cat.No. : BMPR1B-889H
Product Overview : Recombinant Human BMPR1B (Accession # O00238), fused with , was produced in Mouse myeloma cell line, NS0-derived.
Source : NSO Cells
Species : Human
Tag : Fc
Predicted N Terminal : Met
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its ability to inhibit rhBMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al. (1999) Exp. Cell Res. 250:351.The ED50 for this effect is typically 0.5 - 1.5 µg/mL in the presence of 30 ng/mL of rhBMP-4.
Molecular Mass : Recombinant Human BMPR1B, Fc Chimera has a calculated MW of 40 kDa (monomer). In SDS-PAGE migrates as 50-55 kDa, reducing conditions.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : BMPR1B bone morphogenetic protein receptor, type IB [ Homo sapiens ]
Official Symbol : BMPR1B
Synonyms : BMPR1B; bone morphogenetic protein receptor, type IB; bone morphogenetic protein receptor type-1B; ALK6; CDw293; BMPR-1B; BMP type-1B receptor; activin receptor-like kinase 6; serine/threonine receptor kinase; ALK-6;
Gene ID : 658
mRNA Refseq : NM_001203
Protein Refseq : NP_001194
MIM : 603248
UniProt ID : O00238
Chromosome Location : 4q23-q24

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