Active Recombinant Human TPP1 Protein, His-tagged

• Cat.No.: TPP1-925H
• Product Overview: Recombinant Human TPP1 (Accession # O14773) Met1-Pro563, fused with a C-terminal 10-His tag, was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: His
• Predicted N Terminal: Ser20
• Form: Supplied as a 0.2 µm filtered solution in Tris and NaCl.
• Bio-activity: Measured by the cleavage of Ala-Ala-Phe-AMC.The specific activity is >850 pmol/min/µg, as measured under the described conditions.
• Molecular Mass: Recombinant Human TPP1, His-tagged has a calculated MW of 61 kDa. In SDS-PAGE migrates as 65-75 kDa, reducing conditions.
• Protein length: Met1-Pro563
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: TPP1 tripeptidyl peptidase I [ Homo sapiens ]
• Official Symbol: TPP1
• Synonyms: TPP1; tripeptidyl peptidase I; ceroid lipofuscinosis, neuronal 2, late infantile (Jansky Bielschowsky disease) , CLN2; tripeptidyl-peptidase 1; TPP I; tripeptidyl aminopeptidase; growth-inhibiting protein 1; cell growth-inhibiting gene 1 protein; lysosomal pepstatin insensitive protease; CLN2; GIG1; LPIC; TPP-1; MGC21297
• Gene ID: 1200
• mRNA Refseq: NM_000391
• Protein Refseq: NP_000382
• MIM: 607998
• UniProt ID: O14773
• Chromosome Location: 11p15.4