Recombinant Human casein kinase 2, beta polypeptide
Cat.No. : | CSNK2B-23H |
Product Overview : | Recombinant Human Casein Kinase 2 beta is a non-glycosylated polypeptide having a molecular mass of 24.9 kDa. Casein Kinase 2 is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
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Cat. No. : | CSNK2B-23H |
Description : | The Casein kinase 2 (EC 2.7.11.1) is a serine/threonine-selective protein kinase that is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm and other cellular processes. Casein kinase 2 activity has been reported to be activated following Wnt signaling pathway activation. A Pertussis toxin-sensitive G protein and Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase 2. |
Source : | Escherichia Coli. |
Unit Definition : | 1U = 1µmol/min at 37 degree C) using the synthetic peptide RRRDDDSDDD. |
Physical Appearance : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Purity : | Greater than 95% as determined by SDS-PAGE. |
Formulation : | CK2 lyophilized from 25mM Tris-HCl, 500mM NaCl, 1mM DTT, 1mM EDTA, protease inhibitor cocktail, pH 8.5. |
Solubility : | Solubilize in distilled H2O or 50% glycerol. |
Biological Activity : | Specific activity > 1U/mg. |
Storage : | Lyophilized CK2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CK2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles. |
Gene Name : | CSNK2B casein kinase 2, beta polypeptide [ Homo sapiens ] |
Synonyms : | CSNK2B; casein kinase 2, beta polypeptide; G5A; CK2B; CK2N; MGC138222; MGC138224; phosvitin; OTTHUMP00000029063; OTTHUMP00000029064; Casein kinase II beta subunit; alternative name: G5a, phosvitin; CSK2B; OTTHUMP00000029060; Phosvitin |
Gene ID : | 1460 |
mRNA Refseq : | NM_001320 |
Protein Refseq : | NP_001311 |
MIM : | 115441 |
UniProt ID : | P67870 |
Chromosome Location : | 6p21-p12; 6p21.3 |
Pathway : | Adherens junction; Tight junction; Wnt signaling pathway |
Function : | identical protein binding; protein domain specific binding; protein kinase regulator activity; protein serine/threonine kinase activity |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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