Recombinant Human USP3, His-SUMO-tagged

• Cat.No.: USP33-154H
• Product Overview: Recombinant Human USP33core protein, fused with His6-SUMO tag, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&SUMO
• Description: USP33 was originally identified as a protein that interacts with the E3 ubiquitin ligase pVHL, a region commonly mutated in patients with pVHL disease and has been shown to be ubiquitylated by the pVHL E3 ligase complex in vitro and in transiently transfected COS-7 cells. The USP33 catalytic core spans amino acids 181-712.
• Form: Liquid, 25 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM DTT, 10% glycerol
• Molecular Mass: 61kDa
• Storage: Store at -80°C, avoiding repeated freeze-thaw cycles.

Gene Information

• Gene Name: USP33 ubiquitin specific peptidase 33 [ Homo sapiens ]
• Official Symbol: USP33
• Synonyms: USP33; ubiquitin specific peptidase 33; ubiquitin specific protease 33; ubiquitin carboxyl-terminal hydrolase 33; KIAA1097; VDU1; hVDU1; ubiquitin thioesterase 33; deubiquitinating enzyme 33; ubiquitin thiolesterase 33; VHL-interacting deubiquitinating enzyme 1; ubiquitin-specific-processing protease 33; pVHL-interacting deubiquitinating enzyme 1; MGC16868
• Gene ID: 23032
• mRNA Refseq: NM_015017
• Protein Refseq: NP_055832
• UniProt ID: Q8TEY7
• Chromosome Location: 1p31
• Function: G-protein coupled receptor binding; cysteine-type endopeptidase activity; metal ion binding; peptidase activity; protein binding; NOT ubiquitin binding; ubiquitin thiolesterase activity; ubiquitin-specific protease activity; zinc ion binding