"BRD9" Related Products

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Recombinant Human BRD9, His&FLAG-tagged

Cat.No.: BRD9-22H
Product Overview: Recombinant Human BRD9 (130aa-259aa) fussed with His tag N-terminal and FLAG tag at C-terminal was expressed in E. coli.
Description: Bromodomain-containing protein 9 (BRD9) belongs to the BET subclass of proteins, which are characterized by two N-terminal bromodomains and one ET (Extra Terminal) domain. BRDs associate with chromatin through their bromodomains that recognize acetylated histone lysine residues. Bromodomains function as ‘readers’ of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. The ET domain functions as a protein binding motif and exerts atypical serine-kinase activity. The BET family consists of at least four members in mouse and human, BRD2 (also referred to as FSRG1, RING3), BRD3 (FSRG2, ORFX), BRD4 (FSRG4, MCAP/HUNK1), and BRDT (FSRG3, BRD6) that function in the regulation of transcriptional activation and chromatin remodeling. There are five isoforms of BRD9 that are produced by alternative splicing.
Source: E. coli
Species: Human
Tag: His&FLAG
Form: 25 mM Tris pH 7.4, 150 mM NaCl and 5% glycerol
Molecular Mass: 20.9 kDa
Applications: Binding assays, inhibitor screening, and selectivity profiling.
Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80 centigrade to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Concentration: 10 mg/ml
Gene Name: BRD9 bromodomain containing 9 [ Homo sapiens ]
Official Symbol: BRD9
Synonyms: PRO9856; LAVS3040; bromodomain-containing protein 9; rhabdomyosarcoma antigen MU-RMS-40.8; sarcoma antigen NY-SAR-29; FLJ43530; DKFZp434D0711; DKFZp686L0539
Gene ID: 65980
mRNA Refseq: NM_023924
Protein Refseq: NP_076413
UniProt ID: Q9H8M2
Chromosome Location: 5p15.33
Function: lysine-acetylated histone binding; nucleic acid binding; protein binding

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