Active Recombinant Human CD276, Fc-tagged
Cat.No. : | CD276-542H |
Product Overview : | The recombinant human B7-H3-Fc fusion is expressed as a 448 amino acid protein consisting of Leu29 - Ala248 region of B7-H3 (UniProt accession #Q5ZPR3 - isoform 2) and a C-terminal Fc fusion from human IgG1, which exists as a dimer under non-reducing condition. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier free). |
Bio-activity : | Inhibits anti-CD3-induced proliferation of stimulated human T cells. Binds anti-B7-H3 monoclonal antibodies, human IgG1 and rabbit IgG in a functional ELISA. |
Molecular Mass : | Calculated molecular mass 49.2 kDa; estimated by SDS-PAGE under reducing condition 65-70 kDa probably due to glycosylation |
AA Sequence : | LEVQVPEDPVVALVGTDATLCCSFS PEPGFSLAQLNLIWQLTDTKQLVHS FAEGQDQGSAYANRTALFPDLLAQ GNASLRLQRVRVADEGSFTCFVSIR DFGSAAVSLQVAAPYSKPSMTLEPN KDLRPGDTVTITCSSYRGYPEAEV FWQDGQGVPLTGNVTTSQMANEQGL FDVHSVLRVVLGANGTYSCLVRNPV LQQDAHGSVTITGQPMTFPPEAST GTHTCPPCPAPELLGGPSVFLFPPK PKDTLMISRTPEVTCVVVDVSHEDP EVKFNWYVDGVEVHNAKTKPREEQ YNSTYRVVSVLTVLHQDWLNGKEYK CKVSNKALPAPIEKTISKAKGQPRE PQVYTLPPSREEMTKNQVSLTCLV KGFYPSDIAVEWESNGQPENNYKTT PPVLDSDGSFFLYSKLTVDKSRWQQ GNVFSCSVMHEALHNHYTQKSLSL SPGK |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | CD276 CD276 molecule [ Homo sapiens ] |
Official Symbol : | CD276 |
Synonyms : | CD276; CD276 molecule; CD276 antigen; B7 H3; B7H3; B7RP 2; B7 homolog 3; costimulatory molecule; B7-H3; B7RP-2; 4Ig-B7-H3; |
Gene ID : | 80381 |
mRNA Refseq : | NM_001024736 |
Protein Refseq : | NP_001019907 |
MIM : | 605715 |
UniProt ID : | Q5ZPR3 |
Chromosome Location : | 15q23-q24 |
Pathway : | Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; |
Function : | protein binding; receptor binding; |
Products Types
◆ Recombinant Protein | ||
CD276-901R | Recombinant Rat CD276 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD276-601M | Recombinant Mouse CD276 Protein | +Inquiry |
CD276-1238H | Recombinant Human CD276 protein(Met1-Thr243), His-tagged | +Inquiry |
CD276-1287H | Recombinant Human CD276 Protein, Fc-Avi-tagged, Biotinylated | +Inquiry |
CD276-3054H | Recombinant Human CD276 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CD276-001MCL | Recombinant Mouse CD276 cell lysate | +Inquiry |
CD276-826RCL | Recombinant Rat CD276 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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