CD276

  • Official Full Name

    CD276 molecule

  • Overview

    B7-H3 is a member of the B7 gene family. It has 88% amino acid sequence identity with mouse B7-H3. It is mostly expressed on professional APCs, including B cells, macrophages, and dendritic cells. Its expression on dendritic cells appears to be up-regulat
  • Synonyms

    CD276; CD276 molecule; CD276 antigen; B7 H3; B7H3; B7RP 2; B7 homolog 3; costimulatory molecule; B7-H3; B7RP-2; 4Ig-B7-H3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • GMP Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chromatography Reagents
  • Chicken
  • Cynomolgus
  • Cynomolgus Monkey
  • Human
  • Monkey
  • Mouse
  • Rat
  • Rhesus monkey
  • Zebrafish
  • CHO
  • CHO cells
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293T
  • Human Cell
  • Human Cells
  • Mammalian Cell
  • Mammalian cells
  • Avi|Fc
  • C
  • Avi
  • His
  • hFc
  • DDK|His
  • DYKDDDDK
  • Fc
  • GST
  • HIgG1 Fc
  • hIgG4
  • His (Fc)
  • His(C
  • ter)
  • His\Avi
  • His|Flag|StrepII
  • human|IgG1|Fc
  • mFc
  • MIgG2a Fc
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD276-757H Active Recombinant Human CD276 Protein, His-tagged Mammalian cells His
Human CD276-2002H Active Recombinant Human CD276, HIgG1 Fc-tagged CHO Fc
Human CD276-542H Active Recombinant Human CD276, Fc-tagged Human Cell Fc
Human CD276-2001H Active Recombinant Human CD276, MIgG2a Fc-tagged CHO Fc
Human CD276-756H Active Recombinant Human CD276 Protein, Fc Chimera Mammalian cells Fc
Human CD276-543H Active Recombinant Human CD276, Fc-tagged, Biotinylated Human Cell Fc
Human CD276-2002HAF555 Active Recombinant Human CD276 Protein, hFc-tagged, Alexa Fluor 555 conjugated CHO hFc
Human CD276-756HAF555 Active Recombinant Human CD276 Protein, Fc-tagged, Alexa Fluor 555 conjugated Mammalian cells Fc
Human CD276-051H Active Recombinant Human CD276 protein, Fc/Avi-tagged, Biotinylated CHO cells Fc/Avi
Human CD276-053H Active Recombinant Human CD276 protein, Fc/Avi-tagged, Biotinylated CHO cells Fc/Avi
Human CD276-2002HAF647 Active Recombinant Human CD276 Protein, hFc-tagged, Alexa Fluor 647 conjugated CHO hFc
Human CD276-756HAF647 Active Recombinant Human CD276 Protein, Fc-tagged, Alexa Fluor 647 conjugated Mammalian cells Fc
Human CD276-056H Active Recombinant Human CD276 protein, His/Avi-tagged, Biotinylated HEK293 cells His/Avi
Human CD276-2001HAF488 Active Recombinant Human CD276 Protein, MIgG2a mFc-tagged, Alexa Fluor 488 conjugated CHO mFc
Human CD276-2002HF Active Recombinant Human CD276 Protein, hFc-tagged, FITC conjugated CHO hFc
Human CD276-542HF Active Recombinant Human CD276 Protein, Fc-tagged, FITC conjugated HEK293 Fc
Human CD276-2002HAF488 Active Recombinant Human CD276 Protein, hFc-tagged, Alexa Fluor 488 conjugated CHO hFc
Human CD276-542HAF488 Active Recombinant Human CD276 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
Human CD276-756HAF488 Active Recombinant Human CD276 Protein, Fc-tagged, Alexa Fluor 488 conjugated Mammalian cells Fc
Human CD276-756HF Active Recombinant Human CD276 Protein, Fc-tagged, FITC conjugated Mammalian cells Fc
Human CD276-2001HAF555 Active Recombinant Human CD276 Protein, MIgG2a mFc-tagged, Alexa Fluor 555 conjugated CHO mFc
Human CD276-2001HAF647 Active Recombinant Human CD276 Protein, MIgG2a mFc-tagged, Alexa Fluor 647 conjugated CHO mFc
Human CD276-542HAF555 Active Recombinant Human CD276 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
Human CD276-542HAF647 Active Recombinant Human CD276 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
Human CD276-2001HF Active Recombinant Human CD276 Protein, MIgG2a mFc-tagged, FITC conjugated CHO mFc
Human CD276-303H Recombinant Human CD276 protein, Fc-tagged HEK293 human/IgG1/Fc
Human CD276-7674H Recombinant Human CD276 protein, His-tagged E.coli His
Human CD276-0766H Active Recombinant Human CD276 Protein, His-Flag-StrepII-Tagged Human Cell His/Flag/StrepII
Human CD276-10935H Recombinant Human CD276, GST-tagged E.coli GST
Human CD276-4893H Recombinant Human CD276 protein, His-tagged, biotinylated HEK293 His
Human CD276-3884H Recombinant Human CD276 protein, His-tagged HEK293 His
Human CD276-183H Recombinant Human CD276, Fc-tagged CHO Fc
Human CD276-002H Recombinant Human CD276 Protein, DDK/His-tagged HEK293 DDK/His
Human CD276-1959HCL Recombinant Human CD276 cell lysate Human Cell N/A
Human CD276-1287H Recombinant Human CD276 Protein, Fc-Avi-tagged, Biotinylated HEK293 Avi/Fc
Human CD276-756HP Recombinant Human CD276 protein, Fc-tagged, R-PE labeled HEK293 Fc
Human CD276-1286H Active Recombinant Human CD276 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
Human CD276-156H Recombinant Human CD276 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human CD276-127H Recombinant Human CD276 protein, His-Avi-tagged HEK293 His-Avi
Human CD276-183HA Recombinant Human CD276 protein, Fc-tagged, APC labeled CHO Fc
Human CD276-183HAF488 Recombinant Human CD276 Protein, Fc-tagged, Alexa Fluor 488 conjugated CHO Fc
Human CD276-303HAF488 Recombinant Human CD276 Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 hFc
Human CD276-586H Recombinant Human CD276 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CD276-2002HA Recombinant Human CD276 protein, HIgG1 Fc-tagged, APC labeled CHO HIgG1 Fc
Human CD276-2001HA Recombinant Human CD276 protein, MIgG2a Fc-tagged, APC labeled CHO MIgG2a Fc
Human CD276-3884HAF488 Recombinant Human CD276 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
Human CD276-303HAF555 Recombinant Human CD276 Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 hFc
Human CD276-347H Recombinant Human CD276 protein, Fc-tagged HEK293 human/IgG1/Fc
Human CD276-303HA Recombinant Human CD276 protein, Fc-tagged, APC labeled HEK293 Fc
Human CD276-3054H Recombinant Human CD276 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CD276-3884HAF555 Recombinant Human CD276 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
Human CD276-127HG Active GMP Recombinant Human CD276 protein HEK293
Human CD276-348H Recombinant Human CD276 protein, His-tagged HEK293 His
Human CD276-183HP Recombinant Human CD276 protein, Fc-tagged, R-PE labeled CHO Fc
Human CD276-303HAF647 Recombinant Human CD276 Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 hFc
Human CD276-183HAF555 Recombinant Human CD276 Protein, Fc-tagged, Alexa Fluor 555 conjugated CHO Fc
Human CD276-502H Recombinant Human CD276 Protein (ECD) (Met1-Thr461), HIgG1 Fc-tagged, Biotinylated HEK293 HIgG1 Fc
Human CD276-2001HP Recombinant Human CD276 protein, MIgG2a Fc-tagged, R-PE labeled CHO MIgG2a Fc
Human CD276-3884HAF647 Recombinant Human CD276 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
Human CD276-183HF Recombinant Human CD276 Protein, Fc-tagged, FITC conjugated CHO Fc
Human CD276-126HB Recombinant Human CD276 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
Human CD276-2002HP Recombinant Human CD276 protein, HIgG1 Fc-tagged, R-PE labeled CHO HIgG1 Fc
Human CD276-303HF Recombinant Human CD276 Protein, hFc-tagged, FITC conjugated HEK293 hFc
Human CD276-599H Recombinant Human CD276 Protein HEK293
Human CD276-155H Recombinant Human CD276 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human CD276-303HP Recombinant Human CD276 protein, Fc-tagged, R-PE labeled HEK293 Fc
Human CD276-3884HF Recombinant Human CD276 Protein, His-tagged, FITC conjugated HEK293 His
Human CD276-2631H-B Recombinant Human CD276 Protein Pre-coupled Magnetic Beads HEK293
Human CD276-600H Recombinant Human CD276 Protein, Fc-tagged HEK293 Fc
Human CD276-542HP Recombinant Human CD276 protein, Fc-tagged, R-PE labeled HEK293 Fc
Human CD276-27H Recombinant Human CD276 Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter)
Human CD276-2901H Active Recombinant Human CD276 protein, His-tagged, FITC-Labeled HEK293 His
Human CD276-183HAF647 Recombinant Human CD276 Protein, Fc-tagged, Alexa Fluor 647 conjugated CHO Fc
Human CD276-542HA Recombinant Human CD276 protein, Fc-tagged, APC labeled HEK293 Fc
Human CD276-145H Recombinant Human CD276 Protein, C-His-tagged E.coli C-His
Human CD276-1238H Recombinant Human CD276 protein(Met1-Thr243), His-tagged HEK293 C-His
Human CD276-2900H Active Recombinant Human CD276 protein, Fc-tagged, FITC-Labeled HEK293 Fc
Human CD276-756HA Recombinant Human CD276 protein, Fc-tagged, APC labeled Mammalian cells Fc
Human CD276-2631H Recombinant Human CD276 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CD276-1363H Recombinant Human CD276 protein(Met1-Thr461), hFc-tagged, Biotinylated HEK293 C-hFc
Human CD276-2902H Active Recombinant Human CD276 protein, Fc-tagged HEK293 Fc
Human CD276-2906H Active Recombinant Human CD276 protein, Fc-tagged HEK293 Fc
Human CD276-0987M Active CD276 protein-coupled magnetic Beads HEK293
Human CD276-2645H Recombinant Human CD276 Protein (Met1-Thr461), C-His tagged Mammalian cells C-His
Human CD276-02H Recombinant Human CD276 Protein, C-Avi-His tagged, Biotinylated Human Cell C-Avi-His
Human CD276-174H Recombinant Human CD276 Protein, His\Avi-tagged Human Cell His\Avi
Mouse CD276-2881M Active Recombinant Mouse CD276, MIgG2a Fc-tagged CHO Fc
Mouse CD276-2881MAF488 Active Recombinant Mouse CD276 Protein, MIgG2a mFc-tagged, Alexa Fluor 488 conjugated CHO mFc
Mouse CD276-2881MAF647 Active Recombinant Mouse CD276 Protein, MIgG2a mFc-tagged, Alexa Fluor 647 conjugated CHO mFc
Mouse CD276-2881MAF555 Active Recombinant Mouse CD276 Protein, MIgG2a mFc-tagged, Alexa Fluor 555 conjugated CHO mFc
Mouse CD276-2881MF Active Recombinant Mouse CD276 Protein, MIgG2a mFc-tagged, FITC conjugated CHO mFc
Mouse CD276-941M Recombinant Mouse CD276 protein, His-tagged HEK293 His
Mouse Cd276-479M Recombinant Mouse Cd276 protein, His-tagged HEK293 His
Mouse Cd276-7675M Recombinant Mouse Cd276 protein, His-tagged E.coli His
Mouse CD276-001MCL Recombinant Mouse CD276 cell lysate Human Cell N/A
Mouse Cd276-479MAF647 Recombinant Mouse Cd276 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
Mouse CD276-601M Recombinant Mouse CD276 Protein HEK293
Mouse CD276-1287MAF488 Recombinant Mouse Cd276 Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 hFc
Mouse CD276-2881MP Recombinant Mouse CD276 protein, MIgG2a Fc-tagged, R-PE labeled CHO MIgG2a Fc
Mouse CD276-1287MF Recombinant Mouse Cd276 Protein, hFc-tagged, FITC conjugated HEK293 hFc
Mouse CD276-602M Recombinant Mouse CD276 Protein, Fc-tagged HEK293 Fc
Mouse CD276-1287MAF555 Recombinant Mouse Cd276 Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 hFc
Mouse CD276-1287M Recombinant Mouse CD276 protein, Fc-tagged HEK293 human/IgG1/Fc
Mouse Cd276-479MAF488 Recombinant Mouse Cd276 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
Mouse CD276-2905M Active Recombinant Mouse CD276 protein, Fc-tagged HEK293 Fc
Mouse CD276-2881MA Recombinant Mouse CD276 protein, MIgG2a Fc-tagged, APC labeled CHO MIgG2a Fc
Mouse Cd276-479MF Recombinant Mouse Cd276 Protein, His-tagged, FITC conjugated HEK293 His
Mouse CD276-1287MP Recombinant Mouse CD276 protein, Fc-tagged, R-PE labeled HEK293 Fc
Mouse Cd276-5407M Recombinant Mouse Cd276 Protein (Val29-Phe244) Mammalian cells Tag Free
Mouse Cd276-479MAF555 Recombinant Mouse Cd276 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
Mouse CD276-1287MA Recombinant Mouse CD276 protein, Fc-tagged, APC labeled HEK293 Fc
Mouse CD276-1287MAF647 Recombinant Mouse Cd276 Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 hFc
Mouse Cd276-219M Recombinant Mouse Cd276 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat CD276-1243R Recombinant Rat CD276 Protein Mammalian Cell His
Rat Cd276-40R Recombinant Rat Cd276 protein, hFc-tagged HEK293 hFc
Rat Cd276-41R Recombinant Rat Cd276, His tagged Human Cell His
Rat CD276-826RCL Recombinant Rat CD276 cell lysate Human Cell N/A
Rat Cd276-40RAF555 Recombinant Rat Cd276 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
Rat CD276-901R Recombinant Rat CD276 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Cd276-40RAF488 Recombinant Rat Cd276 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
Rat Cd276-40RP Recombinant Rat Cd276 protein, Fc-tagged, R-PE labeled HEK293 Fc
Rat Cd276-41RAF647 Recombinant Rat Cd276 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
Rat Cd276-41RAF555 Recombinant Rat Cd276 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
Rat Cd276-41RAF488 Recombinant Rat Cd276 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
Rat Cd276-40RAF647 Recombinant Rat Cd276 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
Rat Cd276-40RF Recombinant Rat Cd276 Protein, Fc-tagged, FITC conjugated HEK293 Fc
Rat CD276-901R-B Recombinant Rat CD276 Protein Pre-coupled Magnetic Beads HEK293
Rat Cd276-40RA Recombinant Rat Cd276 protein, Fc-tagged, APC labeled HEK293 Fc
Rat Cd276-41RF Recombinant Rat Cd276 Protein, His-tagged, FITC conjugated HEK293 His
Monkey CD276-1235CAF555 Recombinant Monkey CD276 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
Monkey CD276-1235CAF488 Recombinant Monkey CD276 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
Monkey CD276-1235CF Recombinant Monkey CD276 Protein, Fc-tagged, FITC conjugated HEK293 Fc
Monkey CD276-1235CAF647 Recombinant Monkey CD276 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
Rhesus monkey CD276-1516R Recombinant Rhesus Monkey CD276 Protein, hIgG4-tagged HEK293 hIgG4
Cynomolgus CD276-1355C Recombinant Cynomolgus CD276 protein, His-tagged HEK293 His
Cynomolgus Monkey CD276-1235C Recombinant Cynomolgus CD276 Protein, Fc-tagged HEK293 Fc
Zebrafish CD276-5113Z Recombinant Zebrafish CD276 Mammalian Cell His
Chicken CD276-5542C Recombinant Chicken CD276 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CD276 Related Articles
  • CD276 Related Research Area

CD276 involved in several pathways and played different roles in them. We selected most pathways CD276 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with CD276 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)CLDNE;SELP;ITGAM;MPZL1;BLB2;NLGN1;ITGB2L;ITGB1;HLA-DOB

CD276 has several biochemical functions, for example, protein binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD276 itself. We selected most functions CD276 had, and list some proteins which have the same functions with CD276. You can find most of the proteins on our site.

Function Related Protein
protein bindingUBA7;ETL4;NUDT2;SPP1;PPP1R8;PYCRL;KCNJ9;EPN3;ATP4B
receptor bindingNPFFL;CD276;F7;GSTM7;SLC27A2;PVRL3;HTT;Fgf15;SLC39A1

CD276 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD276 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD276.

ganglioside_gm1; cona_canen

Wang, L; Kang, FB; et al. B7-H3-mediated tumor immunology: Friend or foe?. INTERNATIONAL JOURNAL OF CANCER 134:2764-2771(2014).
Lutz, AM; Bachawal, SV; et al. Ultrasound Molecular Imaging in a Human CD276 Expression-Modulated Murine Ovarian Cancer Model. CLINICAL CANCER RESEARCH 20:1313-1322(2014).
  • Q&As
  • Reviews

Q&As (5)

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In which other diseases, besides cancer, is CD276 implicated? 11/29/2022

CD276 has been associated with autoimmune diseases and certain inflammatory conditions. Exploring its role in these diseases may open avenues for therapeutic interventions.

Are there diagnostic applications for CD276 in cancer detection? 10/15/2021

Research suggests that CD276 expression levels may serve as a diagnostic biomarker for certain cancers. Detection methods, such as immunohistochemistry, are being explored to assess CD276 levels in tumor tissues.

How does CD276 influence the tumor microenvironment? 05/07/2020

CD276 can modulate the tumor microenvironment by suppressing immune responses, promoting angiogenesis, and supporting tumor cell survival. Understanding these interactions is crucial for developing targeted therapies.

Are there any ongoing clinical trials focusing on CD276 in cancer patients? 06/20/2016

Yes, several clinical trials are underway to evaluate the safety and efficacy of CD276-targeted therapies in different cancer types. These trials aim to assess the impact on patient outcomes and potential side effects.

How does CD276-targeted therapy differ from traditional cancer treatments? 02/14/2016

CD276-targeted therapy focuses on modulating the immune response against cancer cells, whereas traditional treatments like chemotherapy and radiation target rapidly dividing cells, including both healthy and cancerous cells.

Customer Reviews (3)

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Reviews
03/15/2022

    It has consistently demonstrated high sensitivity and accuracy in detecting and quantifying target molecules, allowing for precise and reliable measurement of analytes in my experimental samples.

    08/06/2021

      Its versatility and reliability make it an excellent choice for research applications, and I highly recommend it to fellow scientists.

      06/03/2021

        The sensitivity and specificity of the CD276 Protein have consistently delivered robust and consistent results, enhancing the efficiency and accuracy of my experimental workflows.

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