"TNFRSF17" Related Products

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Recombinant Human TNFRSF17, Fc-tagged, Biotinylated

Cat.No.: TNFRSF17-552H
Product Overview: The recombinant human BCMA-Fc fusion is expressed as a 281 amino acid protein consisting of Leu2 - Ala54 region of BCMA (UniProt accession #Q02223) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
Source: Human cells
Species: Human
Tag: Fc
Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity: Binds to its ligand APRIL and BAFF. Inhibits APRIL-- and BAFF-mediated signaling activities including NF-κB activation and proliferation of anti--IgM co-stimulated B cells.
Molecular Mass: Calculated molecular mass (kDa): 31.3; Estimated by SDS-PAGE under reducing condition (kDa): ~45
Endotoxin: <0.1 eu per 1 μg of purified recombinant protein determined by the
Purity: >95% judged by SDS-PAGE under reducing condition
Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name: TNFRSF17 tumor necrosis factor receptor superfamily, member 17 [ Homo sapiens ]
Official Symbol: TNFRSF17
Synonyms: TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCMA; tumor necrosis factor receptor superfamily member 17; BCM; CD269; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein;
Gene ID: 608
mRNA Refseq: NM_001192
Protein Refseq: NP_001183
MIM: 109545
UniProt ID: Q02223
Chromosome Location: 16p13.1
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Intestinal immune network for IgA production, organism-specific biosystem; Intestinal immune network for IgA production, conserved biosystem;
Function: receptor activity; tumor necrosis factor-activated receptor activity;

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