"TNFRSF10D" Related Products

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Recombinant Human TNFRSF10D, Fc-tagged, Biotinylated

Cat.No.: TNFRSF10D-562H
Product Overview: The recombinant human DcR2-Fc fusion is expressed as a 382 amino acid protein consisting of Ala56 - Pro209 region of DcR2 (UniProt accession #Q9UBN6) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
Source: Human cells
Species: Human
Tag: Fc
Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity: Binds to its ligand human TRAIL and inhibits TRAIL-mediated signaling activity including TRAIL--induced cytotoxicity.
Molecular Mass: Calculated molecular mass (kDa): 42.1; Estimated by SDS-PAGE under reducing condition (kDa): 50-60
Endotoxin: <0.1 eu per 1 μg of purified recombinant protein determined by the
Purity: >95% judged by SDS-PAGE under reducing condition
Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name: TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain [ Homo sapiens ]
Official Symbol: TNFRSF10D
Synonyms: TNFRSF10D; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily member 10D; CD264; DcR2; TRAILR4; TRUNDD; TRAIL receptor 4; decoy receptor 2; decoy with truncated death domain; TNF receptor-related receptor for TRAIL; TRAIL receptor with a truncated death domain; TNF-related apoptosis-inducing ligand receptor 4; DCR2; TRAIL-R4;
Gene ID: 8793
mRNA Refseq: NM_003840
Protein Refseq: NP_003831
MIM: 603614
UniProt ID: Q9UBN6
Chromosome Location: 8p21
Pathway: Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Direct p53 effectors, organism-specific biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem;
Function: TRAIL binding; binding; receptor activity; transmembrane signaling receptor activity;

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