Native Human Pepsinogen I


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Native Human Pepsinogen I

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Cat.No. : PGA-130H
Product Overview : Native Human Pepsinogen I was purified from Human Gastric Mucosa.
Description : Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of proteins after activation of acidic pH. It is synthesized as isoymogens and are classified into two groups, Pepsinogen I and Pepsinogen II). Human PGA and PGC antigen have been investigated as a possible biomarker for early detection of, Gastric cancer (GC), adenoma (GA) and severe atrophic (diffuse or patchy) corpus gastritis.
Source : Human Gastric Mucosa
Species : Human
Form : Lyophilized from tris-chloride, pH 8.5
Bio-activity : > 500 U/mg protein
Molecular Mass : 45 kDa
Purity : > 90% (SDS-PAGE)
Unit Definition : One unit will produce a change in A280 of 0.001 per minute at pH 2.0 and 37°C, measured as TCA-soluble products from hemoglobin.
Stability : 3 years
Storage : -20 centigrade

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