Active Native Human Pepsinogen I
Cat.No. : | PGA-130H |
Product Overview : | Native Human Pepsinogen I was purified from Human Gastric Mucosa. |
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Description : | Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of proteins after activation of acidic pH. It is synthesized as isoymogens and are classified into two groups, Pepsinogen I and Pepsinogen II). Human PGA and PGC antigen have been investigated as a possible biomarker for early detection of, Gastric cancer (GC), adenoma (GA) and severe atrophic (diffuse or patchy) corpus gastritis. |
Source : | Human Gastric Mucosa |
Species : | Human |
Form : | Lyophilized from tris-chloride, pH 8.5 |
Bio-activity : | > 500 U/mg protein |
Molecular Mass : | 45 kDa |
Purity : | > 90% (SDS-PAGE) |
Unit Definition : | One unit will produce a change in A280 of 0.001 per minute at pH 2.0 and 37°C, measured as TCA-soluble products from hemoglobin. |
Stability : | 3 years |
Storage : | -20 centigrade |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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