Native Human Pepsinogen II

• Cat.No.: PGC-132H
• Product Overview: Native Human Pepsinogen II was purified from Human Gastric Mucosa.

Specification

• Description: Human Pepsinogen(s) PG(s) are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of proteins after activation of acidic pH. Pepsinogen is synthesized as isoymogens and are classified into two groups, I and II.
• Source: Human Gastric Mucosa
• Species: Human
• Form: Liquid
• Molecular Mass: 40 kDa
• Purity: > 90% (SDS-PAGE)
• Unit Definition: One unit will produce a change in A280 of 0.001 per minute at pH 2.0 and 37°C, measured as TCA-soluble products from hemoglobin.
• Stability: 1 year
• Storage: 2-8 centigrade
• Concentration: > 0.5 mg/mL

Gene Information

• Gene Name: PGC progastricsin (pepsinogen C) [ Homo sapiens ]
• Official Symbol: PGC
• Synonyms: PEPC; PGII; gastricsin; pepsin C; pepsinogen C; pepsinogen group II; preprogastricsin
• Gene ID: 5225
• mRNA Refseq: NM_001166424
• Protein Refseq: NP_001159896
• MIM: 169740
• UniProt ID: P20142
• Chromosome Location: 6p21.1
• Function: aspartic-type endopeptidase activity