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Recombinant Human IAPP protein, MYC/DDK-tagged

Cat.No. : IAPP-28H
Product Overview : Recombinant Human IAPP fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells.
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Description : Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
Source : HEK293 cells
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 3.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : IAPP islet amyloid polypeptide [ Homo sapiens ]
Official Symbol : IAPP
Synonyms : DAP; IAP; islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); amylin; diabetes-associated peptide; insulinoma amyloid peptide
Gene ID : 3375
mRNA Refseq : NM_000415
Protein Refseq : NP_000406
MIM : 147940
UniProt ID : P10997
Chromosome Location : 12p12.1
Pathway : Amyloids, organism-specific biosystem; Calcitonin-like ligand receptors, organism-specific biosystem; Disease, organism-specific biosystem
Function : hormone activity; identical protein binding; receptor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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12/31/2022

    In addition to the remarkable quality of the protein, the manufacturer's support extends beyond the provision of the product itself.

    04/08/2021

      The manufacturer's supply management capabilities assure a seamless and continuous provision of the IAPP protein.

      11/27/2017

        With their meticulous documentation and support, I am confident that my utilization of IAPP protein in clinical trials will meet all necessary regulations and guidelines.

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