Recombinant Human GNAI3 protein, MYC/DDK-tagged GNAI3-380H

Recombinant Human GNAI3 protein, MYC/DDK-tagged

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Recombinant Human GNAI3 protein, MYC/DDK-tagged

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Cat.No. : GNAI3-380H
Product Overview : Recombinant Human GNAI3 fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells.
Description : Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.
Source : HEK293 cells
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 40.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 [ Homo sapiens ]
Official Symbol : GNAI3
Synonyms : 87U6; ARCND1; guanine nucleotide-binding protein G(k) subunit alpha; g(i) alpha-3
Gene ID : 2773
mRNA Refseq : NM_006496
Protein Refseq : NP_006487
MIM : 139370
UniProt ID : P08754
Chromosome Location : 1p13
Pathway : ADP signalling through P2Y purinoceptor 12, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Adrenergic signaling in cardiomyocytes, organism-specific biosystem
Function : G-protein beta/gamma-subunit complex binding; GTP binding; GTPase activity

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