Ac-DEVD-AFC DYE-120

Ac-DEVD-AFC

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Ac-DEVD-AFC

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Cat.No. : DYE-120
Description : During apoptosis, activated caspase-3 cleaves several substrates, including poly (ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-AFC is a fluorogenic substrate for activated caspase-3 (Km = 9.7 μM), as well as related caspases. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
Molecular Mass : 729.61
Ex(nm) : 351
Em(nm) : 430
Solvent : DMSO
Storage : Store at -20°C in the dark. Dessicated.

Related Gene

AC0T7AC

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