Ac-DEVD-pNA
Cat.No. : | DYE-123 |
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Description : | During apoptosis, activated caspase-3 cleaves several substrates, including poly (ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-pNA is a para-nitro aniline chromophore cleaved by caspases (Km = 18, 11, 32, 180, and 12 μM for caspases-1, -3, -4, -6, and -7, respectively). It is not cleaved by caspase-2. Cleavage is monitored colorimetrically at 405 nm. |
Molecular Mass : | 638.58 |
Ex(nm) : | 408 |
Solvent : | DMSO |
Storage : | Store at -20°C in the dark. Dessicated. |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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