Ac-IETD-AFC

• Cat.No.: DYE-126

Specification

• Tag: Non
• Description: Ac-IETD-AFC is a fluorogenic substrate that can be cleaved by caspase-8 and related enzymes that recognize the amino acid sequence IETD, including caspase-3 processing enzyme, caspase-10, and granzyme B. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
• Molecular Mass: 729.65
• Ex(nm): 380
• Em(nm): 500
• Solvent: DMSO
• Storage: Store at -20°C in the dark. Dessicated.