Pyronin Y DYE-181

Pyronin Y

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Pyronin Y

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Cat.No. : DYE-181
Description : Pyronin Y is a dye that intercalates and stains RNA red, and has been shown to accumulate in the mitochondria of viable cells. Multidrug-resistant (MDR) Acinetobacter baumannii studies tested inhibition of the efflux pump by measuring the intracellluar accumulation of Pyronin Y and Ethidium bromide (sc-203947). Research shows that at low Pyronin Y concentrations the cytostatic effect is cell arrest in the G1 phase, whereas at high concentrations the cells arrest is in the G2 and S phase. Pyronin Y has been used in combination with Alcian Blue (sc-214517) to asses and study pulmonary diseases, and in combination with Methyl Green (sc-215348) to stain nucleic acids in paraffin sections. Additionally Pyronin Y has been used to measure RNA in flow cytometry.
CAS number : 92-32-0
Molecular Mass : 302.8
Formula : C17H19ClN2O
Ex(nm) : 546
Em(nm) : 549
Solvent : DMSO
Storage : Store at -20°C in the dark. Dessicated.

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